- Screening
- Baseline
- In the process of the treatment
- Uncontrolled infection;
- At the end of the treatment
- Follow-up 1
- Follow-up 2
- Follow-up 3
- Management system of participants
- Speciman management system
- Data management system
- ADR/ADE management system
- Madicine management system
- Instruments management system
- SOPs
- Research team
- Design, Methods
|
Diagnosed as lymphoma with pathological evidences. | yes
|
|
Patients that have indications for APBSCT and are willing to have transplantation; | yes
|
|
Age 18-60 years; | 49 y |
|
ECOG ≤3 | yes
|
|
Normal organ functions should satisfy: | liver function: ALT, AST, TBIL≤ twice of the normal maximum
/renal function: BUN, Cr≤1.5 times of the normal maximum
|
|
No contraindications for chemotherapy | yes
|
|
Patients should sign the written consent before enrollment of the trial, and the written consent should consent all the contents of the trial; | yes
|
|
Willing to follow the therapeutic plan, the follow-up plan and take the corresponding lab examinations | yes
|
|
Contra-indications for chemotherapy | no
|
|
Patients with severe organ impairment: including respiratory failure, heart failure of degree II and beyond, decompensated liver failure, renal failure; uncontrolled hypertention or diabetes, severe diabetic retinal disease; | no
|
|
Use of cytokines beside G-CSF within 3 weeks prior to enrollment | no
|
|
Uncontrolled infection; | no
|
|
History of severe rhTPO allergy | no
|
|
Women during pregnancy or lactation | no
|
|
Patients that are participating other trials | no
|
|
Patients with other severe acute/chronic physical or mental disorders, or with abnormal lab tests that may impair drug administration or influence the researchers’ evaluation, or influence the explanation about the results. | no
|
- Management of the progress
- General information
- Physical examination
- Stage of Disease
- Disease Condition
- Group
- Coagulation Function Tests
- Serum Liver Function Tests
- HBV Markers Test
- Renel Function Test
- Heat Function Examination
- Blood Cell Morphology
- Image Examinations
- Nervous System Examination
- Lung Function Examination
- Blood Gas Analysis
- Physical Ability Examination
- Health Relative Quality of Life
|
Gender | Female
|
|
Age | 49 y |
|
Body Surface Area | 1.342 m2 |
PR
|
Experiment Group
|
|
Total Amount of CD34+ cells collected | 2.74 10^6 |
|
Amount of Mononucleated cells collected | 2.96 10^6 |
- Management for Progress
- Myeloid Linage Inplantation Date
- Blood Routine Tests
- Urine and Stool Routine Tests
- Serum Electrolytes Tests
- Liver Function Tests
- HBV Markers Test
- Renel Function Test
- Heat Function Examination
- Image Examinations
- Blood Cell Morphology
- Nervous System Examination
- Lung Function Examination
- Blood Gas Analysis
- Physical Sbility Examination
- Health Relative Quality of Life
9 d |