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1.Screening
1.2.Inclusion Criteria
1.3.Exclusion Criteria
2.Baseline
1.Body Parameters

Weight

72 kg

Height

1.65 m

Body Mass Index

28.12 kg/m2

Waist Circumference

97 cm

Hip Circumference

107 cm

Waist–hip Ratio

0.90

blood pressure

165/72 mmHg

2.Menstrual Period

Menstruation

3 次/12月

3.Hairy Score and Acne Score

Modified Ferriman and Gallwey Score

0

Rosenfield score

0

4.Oral Glucose Tolerance Test

Fasting Blood Glucose

5.40 mmol/l

0.5h postprandial blood glucose

mmol/l

1h postprandial blood glucose

10.4 mmol/l

2h postprandial blood glucose

10 mmol/l

3h postprandial blood glucose

mmol/l

Area under the curve of glucose

5.Insulin Releasing Test

Fasting Insulin

16.4 mU/L

0.5h postprandial insulin

mU/L

1h postprandial insulin

129.1 mU/L

2h postprandial insulin

206.7 mU/L

3h postprandial insulin

mU/L

Area under the curve of insulin

6.Islet Function Evaluation

The homeostasis model assessment of insulin resistance

3.936

Insulin Secretion Index

7.Blood Lipid Profile

Total Cholesterol

5.69 mmol/l

Triglycerides

1.22 mmol/l

Low-density Lipoprotein

4.46 mmol/l

High-density lipoprotein

1.17 mmol/l

8.Sex Hormones Level

Total Testosterone

1.77 nmol/l

Estradiol

509 nmol/l

Progesterone

0.5 nmol/l

Luteinizing Hormone

17.66 nmol/l

Follicle Stimulating Hormone

7.11 nmol/l

Dehydroepiandrosterone Sulfate

280.1 μg/dl

Sex hormone binding globulin

28.2 nmol/l

LH/FSH Ratio

Free androgen index

9.Inflammatory Marks

High sensitivity C - reactive protein

1.04 mg/L

10.Body Fat Distribution

Android fat mass

45 %

Total fat mass

35 %

3.Follow-up 1
1.Body Parameters

Weight

68 kg

Waist Circumference

86 cm

Hip Circumference

96 cm

Body Mass Index

24.9 kg/m2

Waist–hip Ratio

0.89

2.Adverse Events

No

No

3.Urine pregnancy test

Urine pregnancy test or not

Urine pregnancy test(Positive/Negative)

4.Follow-up 2
1.Body Parameters

Weight

68 kg

Body Mass Index

24.98 kg/m2

Waist Circumference

86 cm

Hip Circumference

96 cm

Waist–hip Ratio

0.89 cm

2.Adverse Events

No

No

3.Urine pregnancy test

Urine pregnancy test or not

Urine pregnancy test(Positive/Negative)

5.Follow-up 3
1.Body Parameters

Weight

65 kg

Body Mass Index

23.8 kg/m2

Waist Circumference

81 cm

Hip Circumference

94 cm

Waist–hip Ratio

0.86

blood pressure

120/83 mmHg

2.Menstrual Period

Menstruation

6 次/3月

3.Hairy Score and Acne Score

Modified Ferriman and Gallwey Score

0

Rosenfield Score

0

4.Oral Glucose Tolerance Test

Fasting blood glucose

4.83 mmol/l

0.5h postprandial blood glucose

mmol/l

1h postprandial blood glucose

mmol/l

2h postprandial blood glucose

6.65 mmol/l

3h postprandial blood glucose

mmol/l

Glucose Area under the Curve

5.Insulin Releasing Test

Fasting Insulin

16.9 mU/L

0.5h postprandial insulin

mU/L

1h postprandial insulin

mU/L

2h postprandial insulin

61 mU/L

3h postprandial insulin

mU/L

Area under the curve of insulin

6.Islet Function Evaluation

The homeostasis model assessment of insulin resistance

3.62

Insulin Secretion Index

7.Blood Lipid Profile

Total cholesterol

6.33 mmol/l

Triglycerides

1.12 mmol/l

Low-density lipoprotein

4.99 mmol/l

High-density lipoprotein

1.08 mmol/l

8.Sex Hormones Level

Total Testosterone

0.91 nmol/l

Estradiol

nmol/l

Progesterone

nmol/l

Luteinizing Hormone

nmol/l

Follicle Stimulating Hormone

nmol/l

Dehydroepiandrosterone sulfate

μg/dl

Sex hormone binding globulin

nmol/l

LH/FSH Ratio

Free androgen index

9.Inflammatory Marks

High sensitivity C - reactive protein

1.08 mg/L

10.Body Fat Distribution

Android fat mass

42 %

Total fat mass

35 %

11.Urine pregnancy test

Urine pregnancy test or not

6.Follow-up 4
1.Body Parameters

Weight

kg

Height

cm

Body mass index

kg/m2

Waist Circumference

cm

Hip Circumference

cm

Waist-hip Ratio

blood pressure

mmHg

2.Adverse Events
3.Urine pregnancy test

Urine pregnancy test or not

Urine pregnancy test(Positive/Negative)

4.Gynecological color doppler ultrasound

Gynecological color doppler ultrasound or not

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

7.Follow-up 5
1.Body Parameters

Weight

kg

Height

cm

Body mass index

kg/m2

Waist Circumference

cm

Hip Circumference

cm

Waist-hip Ratio

blood pressure

mmHg

2.Adverse Events
3.Urine pregnancy test

Urine pregnancy test or not

Urine pregnancy test(Positive/Negative)

4.Gynecological color doppler ultrasound

Gynecological color doppler ultrasound or not

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

8.Follow-up 6
7.8.1、Body Parameters

Weight

kg

Height

cm

Body mass index

kg/m2

Waist Circumference

cm

Hip Circumference

cm

Waist-hip Ratio

blood pressure

mmHg

7.8.2、Adverse Events
7.8.3、Urine pregnancy test

Urine pregnancy test or not

Urine pregnancy test(Positive/Negative)

7.8.4、Gynecological color doppler ultrasound

Gynecological color doppler ultrasound or not

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

9.Extended visit
7.9.1、Gynecological color doppler ultrasound

Gynecological color doppler ultrasound or not

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not