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1.Screening
1.2.Inclusion Criteria
1.3.Exclusion Criteria
2.Baseline
1.Body Parameters

Hip Circumference

107 cm

Waist Circumference

97 cm

Body Mass Index

28.12 kg/m2

Height

1.65 m

Weight

72 kg

blood pressure

165/72 mmHg

Waist–hip Ratio

0.90

2.Menstrual Period

Menstruation

3 次/12月

3.Hairy Score and Acne Score

Rosenfield score

0

Modified Ferriman and Gallwey Score

0

4.Oral Glucose Tolerance Test

Area under the curve of glucose

3h postprandial blood glucose

mmol/l

2h postprandial blood glucose

10 mmol/l

1h postprandial blood glucose

10.4 mmol/l

0.5h postprandial blood glucose

mmol/l

Fasting Blood Glucose

5.40 mmol/l

5.Insulin Releasing Test

3h postprandial insulin

mU/L

2h postprandial insulin

206.7 mU/L

1h postprandial insulin

129.1 mU/L

0.5h postprandial insulin

mU/L

Fasting Insulin

16.4 mU/L

Area under the curve of insulin

6.Islet Function Evaluation

Insulin Secretion Index

The homeostasis model assessment of insulin resistance

3.936

7.Blood Lipid Profile

High-density lipoprotein

1.17 mmol/l

Low-density Lipoprotein

4.46 mmol/l

Triglycerides

1.22 mmol/l

Total Cholesterol

5.69 mmol/l

8.Sex Hormones Level

Sex hormone binding globulin

28.2 nmol/l

Free androgen index

Dehydroepiandrosterone Sulfate

280.1 μg/dl

LH/FSH Ratio

Follicle Stimulating Hormone

7.11 nmol/l

Luteinizing Hormone

17.66 nmol/l

Progesterone

0.5 nmol/l

Estradiol

509 nmol/l

Total Testosterone

1.77 nmol/l

9.Inflammatory Marks

High sensitivity C - reactive protein

1.04 mg/L

10.Body Fat Distribution

Total fat mass

35 %

Android fat mass

45 %

3.Follow-up 1
1.Body Parameters

Waist–hip Ratio

0.89

Body Mass Index

24.9 kg/m2

Hip Circumference

96 cm

Waist Circumference

86 cm

Weight

68 kg

2.Adverse Events

No

No

3.Urine pregnancy test

Urine pregnancy test(Positive/Negative)

Urine pregnancy test or not

4.Follow-up 2
1.Body Parameters

Waist–hip Ratio

0.89 cm

Hip Circumference

96 cm

Waist Circumference

86 cm

Body Mass Index

24.98 kg/m2

Weight

68 kg

2.Adverse Events

No

No

3.Urine pregnancy test

Urine pregnancy test(Positive/Negative)

Urine pregnancy test or not

5.Follow-up 3
1.Body Parameters

blood pressure

120/83 mmHg

Waist–hip Ratio

0.86

Hip Circumference

94 cm

Waist Circumference

81 cm

Body Mass Index

23.8 kg/m2

Weight

65 kg

2.Menstrual Period

Menstruation

6 次/3月

3.Hairy Score and Acne Score

Rosenfield Score

0

Modified Ferriman and Gallwey Score

0

4.Oral Glucose Tolerance Test

Glucose Area under the Curve

3h postprandial blood glucose

mmol/l

2h postprandial blood glucose

6.65 mmol/l

1h postprandial blood glucose

mmol/l

0.5h postprandial blood glucose

mmol/l

Fasting blood glucose

4.83 mmol/l

5.Insulin Releasing Test

Area under the curve of insulin

3h postprandial insulin

mU/L

2h postprandial insulin

61 mU/L

1h postprandial insulin

mU/L

0.5h postprandial insulin

mU/L

Fasting Insulin

16.9 mU/L

6.Islet Function Evaluation

Insulin Secretion Index

The homeostasis model assessment of insulin resistance

3.62

7.Blood Lipid Profile

Total cholesterol

6.33 mmol/l

High-density lipoprotein

1.08 mmol/l

Low-density lipoprotein

4.99 mmol/l

Triglycerides

1.12 mmol/l

8.Sex Hormones Level

Free androgen index

LH/FSH Ratio

Sex hormone binding globulin

nmol/l

Dehydroepiandrosterone sulfate

μg/dl

Follicle Stimulating Hormone

nmol/l

Luteinizing Hormone

nmol/l

Progesterone

nmol/l

Estradiol

nmol/l

Total Testosterone

0.91 nmol/l

9.Inflammatory Marks

High sensitivity C - reactive protein

1.08 mg/L

10.Body Fat Distribution

Total fat mass

35 %

Android fat mass

42 %

11.Urine pregnancy test

Urine pregnancy test or not

6.Follow-up 4
1.Body Parameters

blood pressure

mmHg

Waist-hip Ratio

Hip Circumference

cm

Waist Circumference

cm

Body mass index

kg/m2

Height

cm

Weight

kg

2.Adverse Events
3.Urine pregnancy test

Urine pregnancy test(Positive/Negative)

Urine pregnancy test or not

4.Gynecological color doppler ultrasound

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

Gynecological color doppler ultrasound or not

7.Follow-up 5
1.Body Parameters

Hip Circumference

cm

Waist Circumference

cm

Body mass index

kg/m2

Height

cm

Weight

kg

blood pressure

mmHg

Waist-hip Ratio

2.Adverse Events
3.Urine pregnancy test

Urine pregnancy test(Positive/Negative)

Urine pregnancy test or not

4.Gynecological color doppler ultrasound

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

Gynecological color doppler ultrasound or not

8.Follow-up 6
7.8.1、Body Parameters

blood pressure

mmHg

Waist-hip Ratio

Hip Circumference

cm

Waist Circumference

cm

Body mass index

kg/m2

Height

cm

Weight

kg

7.8.2、Adverse Events
7.8.3、Urine pregnancy test

Urine pregnancy test(Positive/Negative)

Urine pregnancy test or not

7.8.4、Gynecological color doppler ultrasound

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

Gynecological color doppler ultrasound or not

9.Extended visit
7.9.1、Gynecological color doppler ultrasound

Whether Gestational sac, germ tissue and fetal heartbeat be visible in gynecological color doppler ultrasound or not

Gynecological color doppler ultrasound or not