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1.Screening
1.1.Management for Progress
1.2.Inclusion Criteria
1.3.Exclusion Criteria
2.Baseline
2.1.Management of the progress
2.2.General information

Hypertension

YES

Age

69 years

Gender

Female

SCr

55 μmol/L

Blood uric acid

225 μmol/L

Triglycerides

0.66 mmol/L

Total cholesterol

3.68 mmol/L

Low density lipoprotein cholesterol

2.24 mmol/L

Fasting blood glucose

8.9 mmol/L

Hb

135 g/L

Temperature

37.6 degree Celsius

Systolic blood pressure

154 mmHg

Systolic blood pressure

150 mmHg

Systolic blood pressure

156 mmHg

Systolic blood pressure

149 mmHg

Systolic blood pressure

142 mmHg

Systolic blood pressure

137 mmHg

Systolic blood pressure

133 mmHg

Diastolic blood pressure

92 mmHg

Diastolic blood pressure

96 mmHg

Diastolic blood pressure

95 mmHg

Diastolic blood pressure

90 mmHg

Diastolic blood pressure

93 mmHg

Diastolic blood pressure

89 mmHg

Diastolic blood pressure

86 mmHg

Mean arterial blood pressure

113 mmHg

Mean arterial blood pressure

114 mmHg

Mean arterial blood pressure

115 mmHg

Mean arterial blood pressure

110 mmHg

Mean arterial blood pressure

109 mmHg

Mean arterial blood pressure

105 mmHg

Mean arterial blood pressure

102 mmHg

Peripheral oxygen saturation

100 %

Peripheral oxygen saturation

100 %

Peripheral oxygen saturation

100 %

Peripheral oxygen saturation

100 %

Peripheral oxygen saturation

100 %

Peripheral oxygen saturation

100 %

Peripheral oxygen saturation

100 %

2.3.Physical examination
2.4.Blood Routine Tests
2.5.Urine and Stool Routine Tests
2.6.Blood Electrolytes Tests
2.7.Coagulation Function Tests
2.8.Serum Liver Function Tests
2.9.HBV Markers Test
2.10.Renel Function Test
2.11.Heat Function Examination

Central venous pressure

9.3 mmHg

Central venous pressure

9,7 mmHg

Central venous pressure

9.9 mmHg

Central venous pressure

10.3 mmHg

Central venous pressure

10.6 mmHg

Central venous pressure

10.8 mmHg

Central venous pressure

10.9 mmHg

Central venous oxygen saturation

72 %

Central venous oxygen saturation

76 %

Central venous oxygen saturation

76 %

Central venous oxygen saturation

70 %

Central venous oxygen saturation

67 %

Central venous oxygen saturation

63 %

Central venous oxygen saturation

61 %

Heart rate

68 bpm

Heart rate

65 bpm

Heart rate

66 bpm

Heart rate

71 bpm

Heart rate

76 bpm

Heart rate

78 bpm

Heart rate

82 bpm

2.12.Blood Cell Morphology
2.13.Image Examinations
2.14.Nervous System Examination
2.15.Lung Function Examination
2.2.15.2.15.1、Lung mechanical ventilation parameters

Peak airway pressure

17 cmH2O

Peak airway pressure

18 cmH2O

Peak airway pressure

18 cmH2O

Peak airway pressure

20 cmH2O

Peak airway pressure

23 cmH2O

Peak airway pressure

24 cmH2O

Peak airway pressure

27 cmH2O

Mean airway pressure

8 cmH2O

Mean airway pressure

10 cmH2O

Mean airway pressure

9 cmH2O

Mean airway pressure

12 cmH2O

Mean airway pressure

13 cmH2O

Mean airway pressure

15 cmH2O

Mean airway pressure

17 cmH2O

Minute ventilation volume

8.5 L/min

Minute ventilation volume

8.4 L/min

Minute ventilation volume

8.7 L/min

Minute ventilation volume

8.3 L/min

Minute ventilation volume

8.2 L/min

Minute ventilation volume

8.7 L/min

Minute ventilation volume

8.4 L/min

2.16.Blood Gas Analysis
2.17.Physical Ability Examination
2.18.Health Relative Quality of Life
3.In the process of the treatment
3.1.Treatment Record
4.At the end of the treatment
4.1.Management for Progress
4.2.Physical examination
4.3.Blood Routine Tests
4.4.Urine and Stool Routine Tests
4.5.Serum Electrolytes Tests
4.6.Liver Function Tests
4.7.HBV Markers Test
4.8.Renel Function Test
4.9.Heat Function Examination
4.10.Image Examinations
4.11.Blood Cell Morphology
4.12.Nervous System Examination
4.13.Lung Function Examination
4.14.Blood Gas Analysis
4.15.Physical Sbility Examination
4.16.Health Relative Quality of Life
5.Follow-up 1
1.Blood routine test
6.Follow-up 2
7.Follow-up 3
8.Management system of participants
9.Speciman management system
10.Data management system
11.ADR/ADE management system
12.Madicine management system
13.Instruments management system
14.SOPs
14.1.Treatment SOP
14.2.Nursing SOP
14.3.Specimen collection SOP
15.Research team
15.1.Institutions
15.2.Researchers
16.Design, Methods
16.1.Calculation of sample size