- Screening
- Baseline
- At the end of the treatment
- In the process of the treatment
- hospital stay
- Follow-up 1
- Follow-up 2
- Follow-up 3
- Management system of participants
- Speciman management system
- Data management system
- ADR/ADE management system
- Madicine management system
- Instruments management system
- SOPs
- Research team
- Design, Methods
1.Screening
1.2.Inclusion Criteria
|
age | 45 岁 |
|
sign informed consent | yes
|
|
Diagnose of achalasia | yes
|
|
Eckardt score | 5 |
1.3.Exclusion Criteria
|
severe cardiopulmonary diseases | no
|
|
blood coagulation diseases | no
|
|
假性贲门失迟缓症 | no
|
2.Baseline
2.2.General information
|
sex | 1 |
|
age | 45 y |
|
disease duration | 1 y |
|
manometry type | 2 |
2.3.pre-treatment indicators
|
preoperative Eckardt score | 5 |
|
preoperative LES pressure | 42.1 mmHg |
|
preoperative 4sIRP | 19.9 mmHg |
4.At the end of the treatment
|
gas-related complication | no
|
3.In the process of the treatment
3.1.Treatment Record
|
operation duration | 70 min |
|
cardiac arrhythmia | no
|
|
used knife | Hybrid knife
|
4.1.hospital stay
|
hospital stay | 7 d |
5.Follow-up 1
|
GERD Q score | 2 |
|
abnormal acid exposure | no
|
|
Gerd symptom | no
|
|
esophagitis | no
|
|
clinically relevant GERD | no
|
|
Los grade of esophagitis | NA
|
|
postoperative LES pressure | 13.2 mmHg |
|
postoperative 4sIRP | 14.2 |
6.Follow-up 2
|
Postoperatiive Eckardt Score | 0 |
|
follow-up time | 11 month |
7.Follow-up 3
8.Management system of participants
9.Speciman management system
10.Data management system
11.ADR/ADE management system
12.Madicine management system
13.Instruments management system
14.SOPs
14.1.Treatment SOP
14.2.Nursing SOP
14.3.Specimen collection SOP