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1.Baseline
1.1.Inclusion criteria

Inclusion criteria

meet criteria

1.2.Gender

Gender

Male

1.3.Age

Age

67

1.4.History of infection

History of infection

None

1.5.Antibiotic exposure

Antibiotic exposure

No

1.6.Use of glucocorticoids

Use of glucocorticoids

no

1.7.Diabetes history

Diabetes history

No

1.8.Reasons for admission to ICU

Reasons for admission to ICU

Cardiovascular disease

1.9.Coma

Coma

Yes

1.10.APACHEⅡ

APACHEⅡ

22

1.11.GCS

Glasgow coma scale

3

2.Information at the time of VAP diagnosis
2.1.Procalcitonin

Procalcitonin

0.43 μg/L

2.2.Simplified CPIS

Simplified CPIS

3

2.3.sputum culture
2.2.3.2.3.1、multidrug-resistant

Multidrug-resistan

Yes

2.2.3.2.3.2、Semi-quantitative cultures

Semi-quantitative cultures

Moderate

3.Treatment
3.1.Mechanical ventilation

Mechanical ventilation

10 Days

3.2.Tracheotomy

Tracheotomy

Yes

3.3.Highest PCT

Highest PCT

1.17 μg/L

4.Antibiotic discontinuation
4.1.Clinical indicators
4.4.1.4.1.1、Highest temperature

Highest temperature

37.7

4.4.1.4.1.2、Characteristics of tracheal secretions

Characteristics of tracheal secretions

Large

4.4.1.4.1.3、APACHEⅡ

APACHEⅡ

5

4.4.1.4.1.4、Glasgow coma scale

Glasgow coma scale

14

4.4.1.4.1.5、Simplified CPIS

Simplified CPIS

3

4.4.1.4.1.6、Days of antibiotic therapy

Days of antibiotic therapy

11 Days

4.2.Laboratory indicators
4.4.2.4.2.1、Procalcitonin

Procalcitonin

0.48 ug/L

4.4.2.4.2.2、Leucocyte count

Leucocyte count

10 ×109/L

4.4.2.4.2.3、Plasma glucose

Plasma glucose

9.0 mmol/L

4.4.2.4.2.4、Plasma albumin

Plasma albumin

35 g/L

4.4.2.4.2.5、Plasma prealbumin

Plasma prealbumin

295 mg/L

4.4.2.4.2.6、Serum creatinine

Serum creatinine

80 μmol/L

4.4.2.4.2.7、Blood urea nitrogen

Blood urea nitrogen

17 mmol/L

4.4.2.4.2.8、Multidrug-resistant

Multidrug-resistant

Yes

4.4.2.4.2.9、Semi-quantitative cultures

Semi-quantitative cultures

Moderate

5.Clinical outcome
5.1.Length of ICU stay

Length of ICU stay

21 Days

5.2.28-day antibiotic-free days

28-day antibiotic-free days

16 Days

5.3.Infection recurrence

Infection recurrence

No