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1.Baseline
1.1.Inclusion criteria

Inclusion criteria

meet criteria

1.2.Gender

Gender

Male

1.3.Age

Age

48

1.4.History of infection

History of infection

Yes

1.5.Antibiotic exposure

Antibiotic exposure

Yes

1.6.Use of glucocorticoids

Use of glucocorticoids

no

1.7.Diabetes history

Diabetes history

Yes

1.8.Reasons for admission to ICU

Reasons for admission to ICU

Cardiovascular disease

1.9.Coma

Coma

Yes

1.10.APACHEⅡ

APACHEⅡ

22

1.11.GCS

Glasgow coma scale

8

2.Information at the time of VAP diagnosis
2.1.Procalcitonin

Procalcitonin

1.21 μg/L

2.2.Simplified CPIS

Simplified CPIS

5

2.3.sputum culture
2.2.3.2.3.1、multidrug-resistant

Multidrug-resistan

Yes

2.2.3.2.3.2、Semi-quantitative cultures

Semi-quantitative cultures

Moderate

3.Treatment
3.1.Mechanical ventilation

Mechanical ventilation

6 Days

3.2.Tracheotomy

Tracheotomy

Yes

3.3.Highest PCT

Highest PCT

5.81 μg/L

4.Antibiotic discontinuation
4.1.Clinical indicators
4.4.1.4.1.1、Highest temperature

Highest temperature

38.2

4.4.1.4.1.2、Characteristics of tracheal secretions

Characteristics of tracheal secretions

Large purulent

4.4.1.4.1.3、APACHEⅡ

APACHEⅡ

17

4.4.1.4.1.4、Glasgow coma scale

Glasgow coma scale

9

4.4.1.4.1.5、Simplified CPIS

Simplified CPIS

5

4.4.1.4.1.6、Days of antibiotic therapy

Days of antibiotic therapy

27 Days

4.2.Laboratory indicators
4.4.2.4.2.1、Procalcitonin

Procalcitonin

0.29 ug/L

4.4.2.4.2.2、Leucocyte count

Leucocyte count

6.0 ×109/L

4.4.2.4.2.3、Plasma glucose

Plasma glucose

14.7 mmol/L

4.4.2.4.2.4、Plasma albumin

Plasma albumin

35.7 g/L

4.4.2.4.2.5、Plasma prealbumin

Plasma prealbumin

214 mg/L

4.4.2.4.2.6、Serum creatinine

Serum creatinine

65.4 μmol/L

4.4.2.4.2.7、Blood urea nitrogen

Blood urea nitrogen

6.22 mmol/L

4.4.2.4.2.8、Multidrug-resistant

Multidrug-resistant

Yes

4.4.2.4.2.9、Semi-quantitative cultures

Semi-quantitative cultures

Light

5.Clinical outcome
5.1.Length of ICU stay

Length of ICU stay

31 Days

5.2.28-day antibiotic-free days

28-day antibiotic-free days

2 Days

5.3.Infection recurrence

Infection recurrence

Yes