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1.Baseline
1.1.Inclusion criteria

Inclusion criteria

meet criteria

1.2.Gender

Gender

Male

1.3.Age

Age

75

1.4.History of infection

History of infection

None

1.5.Antibiotic exposure

Antibiotic exposure

No

1.6.Use of glucocorticoids

Use of glucocorticoids

no

1.7.Diabetes history

Diabetes history

No

1.8.Reasons for admission to ICU

Reasons for admission to ICU

Neurological disease

1.9.Coma

Coma

Yes

1.10.APACHEⅡ

APACHEⅡ

22

1.11.GCS

Glasgow coma scale

4

2.Information at the time of VAP diagnosis
2.1.Procalcitonin

Procalcitonin

0.26 μg/L

2.2.Simplified CPIS

Simplified CPIS

5

2.3.sputum culture
2.2.3.2.3.1、multidrug-resistant

Multidrug-resistan

No

2.2.3.2.3.2、Semi-quantitative cultures

Semi-quantitative cultures

Light

3.Treatment
3.1.Mechanical ventilation

Mechanical ventilation

3 Days

3.2.Tracheotomy

Tracheotomy

Yes

3.3.Highest PCT

Highest PCT

0.26 μg/L

4.Antibiotic discontinuation
4.1.Clinical indicators
4.4.1.4.1.1、Highest temperature

Highest temperature

37.5

4.4.1.4.1.2、Characteristics of tracheal secretions

Characteristics of tracheal secretions

Large

4.4.1.4.1.3、APACHEⅡ

APACHEⅡ

17

4.4.1.4.1.4、Glasgow coma scale

Glasgow coma scale

8

4.4.1.4.1.5、Simplified CPIS

Simplified CPIS

3

4.4.1.4.1.6、Days of antibiotic therapy

Days of antibiotic therapy

14 Days

4.2.Laboratory indicators
4.4.2.4.2.1、Procalcitonin

Procalcitonin

0.23 ug/L

4.4.2.4.2.2、Leucocyte count

Leucocyte count

12.4 ×109/L

4.4.2.4.2.3、Plasma glucose

Plasma glucose

5.9 mmol/L

4.4.2.4.2.4、Plasma albumin

Plasma albumin

25.8 g/L

4.4.2.4.2.5、Plasma prealbumin

Plasma prealbumin

140 mg/L

4.4.2.4.2.6、Serum creatinine

Serum creatinine

63 μmol/L

4.4.2.4.2.7、Blood urea nitrogen

Blood urea nitrogen

7.27 mmol/L

4.4.2.4.2.8、Multidrug-resistant

Multidrug-resistant

No

4.4.2.4.2.9、Semi-quantitative cultures

Semi-quantitative cultures

Rare

5.Clinical outcome
5.1.Length of ICU stay

Length of ICU stay

18 Days

5.2.28-day antibiotic-free days

28-day antibiotic-free days

13 Days

5.3.Infection recurrence

Infection recurrence

No