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1.Baseline
1.1.Inclusion criteria

Inclusion criteria

meet criteria

1.2.Gender

Gender

Female

1.3.Age

Age

75

1.4.History of infection

History of infection

Yes

1.5.Antibiotic exposure

Antibiotic exposure

Yes

1.6.Use of glucocorticoids

Use of glucocorticoids

no

1.7.Diabetes history

Diabetes history

Yes

1.8.Reasons for admission to ICU

Reasons for admission to ICU

Neurological disease

1.9.Coma

Coma

Yes

1.10.APACHEⅡ

APACHEⅡ

31

1.11.GCS

Glasgow coma scale

6

2.Information at the time of VAP diagnosis
2.1.Procalcitonin

Procalcitonin

0.5 μg/L

2.2.Simplified CPIS

Simplified CPIS

6

2.3.sputum culture
2.2.3.2.3.1、multidrug-resistant

Multidrug-resistan

Yes

2.2.3.2.3.2、Semi-quantitative cultures

Semi-quantitative cultures

Moderate

3.Treatment
3.1.Mechanical ventilation

Mechanical ventilation

17 Days

3.2.Tracheotomy

Tracheotomy

Yes

3.3.Highest PCT

Highest PCT

0.5 μg/L

4.Antibiotic discontinuation
4.1.Clinical indicators
4.4.1.4.1.1、Highest temperature

Highest temperature

37.5

4.4.1.4.1.2、Characteristics of tracheal secretions

Characteristics of tracheal secretions

Large

4.4.1.4.1.3、APACHEⅡ

APACHEⅡ

20

4.4.1.4.1.4、Glasgow coma scale

Glasgow coma scale

6

4.4.1.4.1.5、Simplified CPIS

Simplified CPIS

4

4.4.1.4.1.6、Days of antibiotic therapy

Days of antibiotic therapy

17 Days

4.2.Laboratory indicators
4.4.2.4.2.1、Procalcitonin

Procalcitonin

0.3 ug/L

4.4.2.4.2.2、Leucocyte count

Leucocyte count

7.3 ×109/L

4.4.2.4.2.3、Plasma glucose

Plasma glucose

7.1 mmol/L

4.4.2.4.2.4、Plasma albumin

Plasma albumin

26.3 g/L

4.4.2.4.2.5、Plasma prealbumin

Plasma prealbumin

58 mg/L

4.4.2.4.2.6、Serum creatinine

Serum creatinine

39.6 μmol/L

4.4.2.4.2.7、Blood urea nitrogen

Blood urea nitrogen

7.62 mmol/L

4.4.2.4.2.8、Multidrug-resistant

Multidrug-resistant

Yes

4.4.2.4.2.9、Semi-quantitative cultures

Semi-quantitative cultures

Moderate

5.Clinical outcome
5.1.Length of ICU stay

Length of ICU stay

60 Days

5.2.28-day antibiotic-free days

28-day antibiotic-free days

10 Days

5.3.Infection recurrence

Infection recurrence

No