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1.Baseline
1.1.Inclusion criteria

Inclusion criteria

meet criteria

1.2.Gender

Gender

Male

1.3.Age

Age

23

1.4.History of infection

History of infection

None

1.5.Antibiotic exposure

Antibiotic exposure

No

1.6.Use of glucocorticoids

Use of glucocorticoids

no

1.7.Diabetes history

Diabetes history

No

1.8.Reasons for admission to ICU

Reasons for admission to ICU

Traumatic shock

1.9.Coma

Coma

Yes

1.10.APACHEⅡ

APACHEⅡ

21

1.11.GCS

Glasgow coma scale

6

2.Information at the time of VAP diagnosis
2.1.Procalcitonin

Procalcitonin

2.79 μg/L

2.2.Simplified CPIS

Simplified CPIS

6

2.3.sputum culture
2.2.3.2.3.1、multidrug-resistant

Multidrug-resistan

Yes

2.2.3.2.3.2、Semi-quantitative cultures

Semi-quantitative cultures

Heavy

3.Treatment
3.1.Mechanical ventilation

Mechanical ventilation

6 Days

3.2.Tracheotomy

Tracheotomy

Yes

3.3.Highest PCT

Highest PCT

2.79 μg/L

4.Antibiotic discontinuation
4.1.Clinical indicators
4.4.1.4.1.1、Highest temperature

Highest temperature

37.4

4.4.1.4.1.2、Characteristics of tracheal secretions

Characteristics of tracheal secretions

Large purulent

4.4.1.4.1.3、APACHEⅡ

APACHEⅡ

7

4.4.1.4.1.4、Glasgow coma scale

Glasgow coma scale

9

4.4.1.4.1.5、Simplified CPIS

Simplified CPIS

5

4.4.1.4.1.6、Days of antibiotic therapy

Days of antibiotic therapy

15 Days

4.2.Laboratory indicators
4.4.2.4.2.1、Procalcitonin

Procalcitonin

0.25 ug/L

4.4.2.4.2.2、Leucocyte count

Leucocyte count

14.2 ×109/L

4.4.2.4.2.3、Plasma glucose

Plasma glucose

5 mmol/L

4.4.2.4.2.4、Plasma albumin

Plasma albumin

32.9 g/L

4.4.2.4.2.5、Plasma prealbumin

Plasma prealbumin

160 mg/L

4.4.2.4.2.6、Serum creatinine

Serum creatinine

60.1 μmol/L

4.4.2.4.2.7、Blood urea nitrogen

Blood urea nitrogen

4.26 mmol/L

4.4.2.4.2.8、Multidrug-resistant

Multidrug-resistant

Yes

4.4.2.4.2.9、Semi-quantitative cultures

Semi-quantitative cultures

Heavy

5.Clinical outcome
5.1.Length of ICU stay

Length of ICU stay

80 Days

5.2.28-day antibiotic-free days

28-day antibiotic-free days

13 Days

5.3.Infection recurrence

Infection recurrence

No