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1.Screening
1.1.Management for Progress

Serial number

181

Group number

3

Inpatient number

149357

1.2.Inclusion Criteria

Inclusion criteria

yes

1.3.Exclusion Criteria

Exclusion Criteria

no

2.Baseline
2.2.General information

Age at admission

61

Gender

Male

Date of injury:

2015-12-24 yyyy-mm-dd

Time of injury:

9:25 hh:mm

Date of admission:

2015-12-24 yyyy-mm-dd

Time of admission:

10:00 hh:mm

2.3.Physical examination

Dilatation of pupil

Unilateral

First APACHE II score after admission

30

First Glasgow Coma Score after admission

3

2.6.Blood Electrolytes Tests

First blood glucose test after admission

19.50 mmol/L

Glycosylated hemoglobin before surgery

6.50 %

Serum Insulin before surgery

18.45 µU/ml

2.13.Image Examinations

Diagnosis of head CT after admission

Brain contusion

Intracranial hemorrhage measured by head CT

50 ml

3.In the process of the treatment
3.1.Treatment Record

Date of surgery

2015-12-24 yyyy-mm-dd

Time to start surgery

11:35 hh:mm

Date of end of surgery

2015-12-24 yyyy-mm-dd

Time to end surgery

15:40 hh:mm

Surgical site

bilateral

Intraoperative detection of cerebrospinal fluid glucose

5.60 mmol/L

Intraoperative detection of Cerebrospinal fluid Chloride

138.17 mmol/L

Intraoperative detection of Cerebrospinal fluid BUN

5.02 mmol/L

Intraoperative detection of Cerebrospinal fluid Creatinine

43.64 mmol/L

Intraoperative detection of Cerebrospinal fluid LacticAcid

4.52 mmol/L

Blood glucose after surgery

17.30 mmol/L

Blood glucose at 2 hours after operation

10.60 mmol/L

Blood glucose at 4 hours after operation

8.20 mmol/L

Blood glucose at 6 hours after operation

6.90 mmol/L

Blood glucose at 8 hours after operation

6.20 mmol/L

Blood glucose at 10 hours after operation

6.10 mmol/L

Blood glucose at 12 hours after operation

6.20 mmol/L

Blood glucose at 14 hours after operation

6.40 mmol/L

Blood glucose at 16 hours after operation

5.70 mmol/L

Blood glucose at 18 hours after operation

6.30 mmol/L

Blood glucose at 20 hours after operation

6.50 mmol/L

Blood glucose at 22 hours after operation

6.90 mmol/L

Blood glucose at 24 hours after operation

6.50 mmol/L

Blood glucose at 26 hours after operation

6.70 mmol/L

Blood glucose at 28 hours after operation

6.30 mmol/L

Blood glucose at 30 hours after operation

7.00 mmol/L

Blood glucose at 32 hours after operation

6.70 mmol/L

Blood glucose at 34 hours after operation

6.50 mmol/L

Blood glucose at 36 hours after operation

6.70 mmol/L

Blood glucose at 38 hours after operation

6.10 mmol/L

Blood glucose at 40 hours after operation

5.90 mmol/L

Blood glucose at 42 hours after operation

5.60 mmol/L

Blood glucose at 44 hours after operation

5.60 mmol/L

Blood glucose at 46 hours after operation

5.70 mmol/L

Blood glucose at 48 hours after operation

6.30 mmol/L

Blood glucose at 50 hours after operation

5.10 mmol/L

Blood glucose at 52 hours after operation

5.70 mmol/L

Blood glucose at 54 hours after operation

5.70 mmol/L

Blood glucose at 56 hours after operation

5.70 mmol/L

Blood glucose at 58 hours after operation

5.10 mmol/L

Blood glucose at 60 hours after operation

5.60 mmol/L

Blood glucose at 62 hours after operation

5.10 mmol/L

Blood glucose at 64 hours after operation

5.60 mmol/L

Blood glucose at 66 hours after operation

5.50 mmol/L

Blood glucose at 68 hours after operation

4.70 mmol/L

Blood glucose at 70 hours after operation

5.50 mmol/L

Blood glucose at 72 hours after operation

5.40 mmol/L

Blood glucose at 74 hours after operation

5.50 mmol/L

Blood glucose at 76 hours after operation

5.00 mmol/L

Blood glucose at 78 hours after operation

5.10 mmol/L

Blood glucose at 80 hours after operation

5.60 mmol/L

Blood glucose at 82 hours after operation

4.50 mmol/L

Blood glucose at 84 hours after operation

4.90 mmol/L

Blood glucose at 86 hours after operation

4.70 mmol/L

Blood glucose at 88 hours after operation

5.10 mmol/L

Blood glucose at 90 hours after operation

4.00 mmol/L

Blood glucose at 92 hours after operation

4.40 mmol/L

Blood glucose at 94 hours after operation

4.90 mmol/L

Blood glucose at 96 hours after operation

8.30 mmol/L

Blood glucose at 98 hours after operation

9.90 mmol/L

Blood glucose at 100 hours after operation

9.10 mmol/L

Blood glucose at 102 hours after operation

7.50 mmol/L

Blood glucose at 104 hours after operation

9.00 mmol/L

Blood glucose at 106 hours after operation

8.20 mmol/L

Blood glucose at 108 hours after operation

8.70 mmol/L

Blood glucose at 110 hours after operation

9.50 mmol/L

Blood glucose at 112 hours after operation

8.80 mmol/L

Blood glucose at 114 hours after operation

9.60 mmol/L

Blood glucose at 116 hours after operation

8.80 mmol/L

Blood glucose at 118 hours after operation

9.70 mmol/L

Blood glucose at 120 hours after operation

6.90 mmol/L

Blood glucose at 122 hours after operation

4.00 mmol/L

Blood glucose at 124 hours after operation

6.70 mmol/L

Blood glucose at 126 hours after operation

6.80 mmol/L

Blood glucose at 128 hours after operation

6.90 mmol/L

Blood glucose at 130 hours after operation

6.90 mmol/L

Blood glucose at 132 hours after operation

6.60 mmol/L

Blood glucose at 134 hours after operation

6.80 mmol/L

Blood glucose at 136 hours after operation

6.00 mmol/L

Blood glucose at 138 hours after operation

6.10 mmol/L

Blood glucose at 140 hours after operation

6.20 mmol/L

Blood glucose at 142 hours after operation

6.10 mmol/L

Blood glucose at 144 hours after operation

7.80 mmol/L

Blood glucose at 146 hours after operation

9.70 mmol/L

Blood glucose at 148 hours after operation

8.80 mmol/L

Blood glucose at 150 hours after operation

9.60 mmol/L

Blood glucose at 152 hours after operation

9.90 mmol/L

Blood glucose at 154 hours after operation

9.20 mmol/L

Blood glucose at 156 hours after operation

9.50 mmol/L

Blood glucose at 158 hours after operation

9.60 mmol/L

Blood glucose at 160 hours after operation

9.90 mmol/L

Blood glucose at 162 hours after operation

9.20 mmol/L

Blood glucose at 164 hours after operation

9.70 mmol/L

Blood glucose at 166 hours after operation

9.00 mmol/L

Blood glucose at 168 hours after operation

9.50 mmol/L

Insulin pathway

Venous pump

Insulin doses of first day after surgery

61.00 U

Insulin doses of second days after surgery

41.00 U

Insulin doses of third day after surgery

37.00 U

Insulin doses of fourth days after surgery

14.00 U

Insulin doses of fifth day after surgery

10.00 U

Insulin doses of sixth days after surgery

7.00 U

Insulin doses of seventh days after surgery

0.00 U

4.At the end of the treatment
4.1.Management for Progress

ICU length of stay

Discharge date

yyyy-mm-dd

Hospital length of stay

4.5.Serum Electrolytes Tests

Blood glucose 1 week after surgery

mmol/L

Serum Insulin 1 week after surgery

µU/ml

Glycosylated hemoglobin 1 week after surgery

%

Cerebrospinal fluid Glucose 1 week after surgery

mmol/L

Cerebrospinal fluid Chloride 1 week after surgery

mmol/L

Cerebrospinal fluid BUN 1 week after surgery

mmol/L

Cerebrospinal fluid Creatinine 1 week after surgery

mmol/L

Cerebrospinal fluid LacticAcid 1 week after sugery

mmol/L

Blood glucose 2 weeks after surgery

mmol/L

Serum Insulin 2 weeks after surgery

µU/ml

Glycosylated hemoglobin 2 weeks after surgery

%

4.12.Nervous System Examination

Glasgow coma score 1 week after surgery

APCHE II 1 week after surgery

Glasgow coma score 2 weeks after surgery

APCHE II 2 weeks after surgery

5.Follow-up 1

1 month Barthel index

95

1 month modified Rankin Scale

2

1 month Glasgow outcome score

5

6.Follow-up 2

3 months Barthel index

95

3 months modified Rankin Scale

1

3 months Glasgow outcome score

5

7.Follow-up 3

6 months Barthel index

95

6 months Glasgow outcome score

5

Date of last follow-up

2016-07-03 yyyy-mm-dd

Days of follow-up

192

Survival situation

Survival

8.Management system of participants

Complete test

complete

10.Data management system

Data management

Data analysis

11.ADR/ADE management system

The number of blood glucose tests after operation

85

Common adverse events - hypoglycemia (<4.4mmol/L) happen times

2

Common adverse events - Hyperglycemia (>13mmol/L) happen times

1

Serious adverse events

no