1.Screening
1.1.Inclusion Criteria
1.1.1.1.1.1、The study group inclusion criteria
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Patients who meet the following four points: |
1.1.1.1.1.2、The control group inclusion criteria
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The normal volunteers in the group met the following points: |
1.2.Exclusion Criteria
1.1.2.1.2.1、The study group exclusion criteriae study group inclusion criteria
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The patient satisfies one or more of the following: |
1.1.2.1.2.2、The control group exclusion criteria
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Patients meet one or more of the following criteria |
2.Baseline
2.1.DW-MRI
2.2.1.2.1.1、ADC from monoexponential model
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ADC | ×10−3 mm2/s. |
2.2.1.2.1.2、Dt from biexponential model
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true diffusion coefficient，Dt | ×10−3 mm2/s. |
2.2.1.2.1.3、Dp from biexponential model
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pseudo diffusion coefficient，Dp | ×10−3 mm2/s. |
2.2.1.2.1.4、f from biexponential model
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fraction of perfusion，f |
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2.2.1.2.1.5、DDC from stretched-exponential model
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distributed diffusion coefficient， DDC | ×10−3 mm2/s. |
2.2.1.2.1.6、Alpha from stretched-exponential model
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Alpha，α |
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2.2.The liver biopsy of the study group
2.2.2.2.2.1、hepatic fibrosis stages
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Liver fibrosis staging criteria |
2.2.2.2.2.2、inflammatory activity grades
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The liver inflammatory activity classification standard |
3.Research team
3.1.Institutions
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Institutions of the researchers |
3.2.Researchers
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Researchers |