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1.Screening
1.1.Management for Progress
1.2.Inclusion Criteria
1.3.Exclusion Criteria
2.Metabolic and endocrine data

Luteinizing hormone

mIU/ml

Follicle stimulating hormone

mIU/ml

Progesterone

nmol/ml

Estradiol

pmol/ml

Prolactin

ng/ml

Total testosterone

ng/dl (nmol/L)

Blood glucose

mmol/L

Triglycerides

mmol/L

Total cholesterol

mmol/L

High density lipoprotein cholesterol

mmol/L

Low density lipoprotein cholesterol

mmol/L

insulin

2.Bone density

Upper limbs bone mass

g

Thigh bone mass

g

Trunk bone mass

g

Android bone mass

g

Gynoid bone mass

g

Total bone mass

g

L1 BMD

g/cm2

L2 BMD

g/cm2

L3 BMD

g/cm2

L4 BMD

g/cm2

L1 BMC

g

L2 BMC

g

L3 BMC

g

L4 BMC

g

L1 area

cm2

L2 area

cm2

L3 area

cm2

L4 area

cm2

T value of L1

T value of L2

T value of L3

T value of L4

cranium BMD

g/cm2

Upper limbs BMD

g/cm2

Thigh BMD

g/cm2

Trunk BMD

g/cm2

Rib BMD

g/cm2

Pelvis BMD

g/cm2

vertebral column BMD

g/cm2

Total BMD

g/cm2

cranium BMC

g

Upper limbs BMC

g

Thigh BMC

g

Trunk BMC

g

Rib BMC

g

Pelvis BMC

g

vertebral column BMC

g

Total BMC

g

cranium area

cm2

Upper limbs area

cm2

Thigh area

cm2

Trunk bone area

cm2

Rib area

cm2

Pelvis bone area

cm2

vertebral column area

cm2

Total bone area

cm2

cervical vertebra BMD

g/cm2

upper part of the femoral neck BMD

g/cm2

lower part of the femoral neck BMD

g/cm2

Ward's triangle BMD

g/cm2

trochanteric femur BMD

g/cm2

shaft of femur BMD

g/cm2

femur BMD

g/cm2

cervical vertebra BMC

g

upper part of the femoral neck BMC

g

lower part of the femoral neck BMC

g

Ward's triangle BMC

g

trochanteric femur BMC

g

shaft of femur BMC

g

femur BMC

g

cervical vertebra BCA

cm2

upper part of the femoral neck BCA

cm2

lower part of the femoral neck BCA

cm2

trochanteric femur BCA

cm2

Ward's triangle BCA

cm2

shaft of femur BCA

cm2

femur BCA

cm2

cervical vertebra T value

upper part of the femoral neck T value

lower part of the femoral neck T value

Ward's triangle T value

trochanteric femur T value

shaft of femur T value

femur T value

2.Body composition

Trunk muscle mass

g

Android muscle mass

g

Gynoid muscle mass

g

Total muscle mass

g

Upper limbs mass

g

Thigh mass

g

Trunk mass

g

Android mass

g

VAT mass

g

VAT volume

cm2

Upper limbs fat mass

g

Thigh fat mass

g

Trunk fat mass

g

Android fat mass

g

Gynoid fat mass

g

Total fat mass

g

Upper limbs muscle mass

g

Thigh muscle mass

g

2.Baseline
2.1.Management of the progress
2.2.General information

ID

440

Smoking

No

Alcoholic

No

history of fracture

yes

history of diabetes

no

history of cardiovascular disease

no

other diseases

-

history of inherited diseases

no

history of hypertention

no

2.3.Physical examination

Systolic blood pressure

109 mmHg

Diastolic blood pressure

65 mmHg

Weight

56.7 kg

Hight

162.5 cm

Waist

72 cm

Hipline

93 cm

2.4.Blood Routine Tests
2.5.Urine and Stool Routine Tests
2.6.Blood Electrolytes Tests
2.7.Coagulation Function Tests
2.8.Serum Liver Function Tests

ALT

16.2 IU/L

AST

21.2 IU/L

2.9.HBV Markers Test
2.10.Renel Function Test

Creatinine

67.5 umol/L

Urea nitrogen

3.39

UA

252.4 mmol/l

2.11.Heat Function Examination
2.12.Blood Cell Morphology
2.13.Image Examinations
2.14.Nervous System Examination
2.15.Lung Function Examination
2.16.Blood Gas Analysis
2.17.Physical Ability Examination
2.18.Health Relative Quality of Life
3.In the process of the treatment
3.1.Treatment Record
4.At the end of the treatment
4.1.Management for Progress
4.2.Physical examination
4.3.Blood Routine Tests
4.4.Urine and Stool Routine Tests
4.5.Serum Electrolytes Tests
4.6.Liver Function Tests
4.7.HBV Markers Test
4.8.Renel Function Test
4.9.Heat Function Examination
4.10.Image Examinations
4.11.Blood Cell Morphology
4.12.Nervous System Examination
4.13.Lung Function Examination
4.14.Blood Gas Analysis
4.15.Physical Sbility Examination
4.16.Health Relative Quality of Life
5.Follow-up 1
1.Blood routine test
6.Follow-up 2
7.Follow-up 3
8.Management system of participants
9.Speciman management system
10.Data management system
11.ADR/ADE management system
12.Madicine management system
13.Instruments management system
14.SOPs
14.1.Treatment SOP
14.2.Nursing SOP
14.3.Specimen collection SOP
15.Research team
15.1.Institutions
15.2.Researchers
16.Design, Methods
16.1.Calculation of sample size