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1.Screening
1.1.Management for Progress
1.2.Inclusion Criteria
1.3.Exclusion Criteria
2.Metabolic and endocrine data

Luteinizing hormone

mIU/ml

Follicle stimulating hormone

mIU/ml

Progesterone

nmol/ml

Estradiol

pmol/ml

Prolactin

ng/ml

Total testosterone

ng/dl (nmol/L)

Blood glucose

mmol/L

Triglycerides

mmol/L

Total cholesterol

mmol/L

High density lipoprotein cholesterol

mmol/L

Low density lipoprotein cholesterol

mmol/L

insulin

2.Bone density

L2 BMC

g

Pelvis BMD

g/cm2

Pelvis bone area

cm2

femur BMC

g

L1 BMC

g

Rib BMD

g/cm2

Rib area

cm2

shaft of femur BMC

g

L4 BMC

g

Total BMD

g/cm2

Total bone area

cm2

upper part of the femoral neck BCA

cm2

lower part of the femoral neck T value

L3 BMC

g

vertebral column BMD

g/cm2

vertebral column area

cm2

cervical vertebra BCA

cm2

L1 area

cm2

cranium BMC

g

cervical vertebra BMD

g/cm2

lower part of the femoral neck BCA

cm2

Ward's triangle T value

L2 area

cm2

Upper limbs BMC

g

upper part of the femoral neck BMD

g/cm2

trochanteric femur BCA

cm2

trochanteric femur T value

Thigh bone mass

g

L4 area

cm2

Trunk BMC

g

Ward's triangle BMD

g/cm2

shaft of femur BCA

cm2

femur T value

Upper limbs bone mass

g

L3 area

cm2

Thigh BMC

g

lower part of the femoral neck BMD

g/cm2

Ward's triangle BCA

cm2

shaft of femur T value

L4 BMD

g/cm2

Trunk BMD

g/cm2

Trunk bone area

cm2

trochanteric femur BMC

g

L3 BMD

g/cm2

Thigh BMD

g/cm2

Thigh area

cm2

Ward's triangle BMC

g

L2 BMD

g/cm2

Upper limbs BMD

g/cm2

Upper limbs area

cm2

lower part of the femoral neck BMC

g

L1 BMD

g/cm2

cranium BMD

g/cm2

cranium area

cm2

upper part of the femoral neck BMC

g

Total bone mass

g

T value of L4

Total BMC

g

cervical vertebra BMC

g

Gynoid bone mass

g

T value of L3

vertebral column BMC

g

femur BMD

g/cm2

upper part of the femoral neck T value

Android bone mass

g

T value of L2

Pelvis BMC

g

shaft of femur BMD

g/cm2

cervical vertebra T value

Trunk bone mass

g

T value of L1

Rib BMC

g

trochanteric femur BMD

g/cm2

femur BCA

cm2

2.Body composition

Thigh muscle mass

g

Upper limbs muscle mass

g

Trunk muscle mass

g

Gynoid muscle mass

g

Android muscle mass

g

Total fat mass

g

Gynoid fat mass

g

Android fat mass

g

Trunk fat mass

g

Android mass

g

Thigh fat mass

g

Trunk mass

g

Upper limbs fat mass

g

Thigh mass

g

VAT volume

cm2

Upper limbs mass

g

VAT mass

g

Total muscle mass

g

2.Baseline
2.1.Management of the progress
2.2.General information

ID

448

Smoking

No

Alcoholic

No

history of fracture

yes

history of diabetes

no

history of hypertention

no

history of inherited diseases

no

other diseases

-

history of cardiovascular disease

no

2.3.Physical examination

Systolic blood pressure

111 mmHg

Diastolic blood pressure

62 mmHg

Weight

54.4 kg

Hight

159 cm

Waist

71 cm

Hipline

89 cm

2.4.Blood Routine Tests
2.5.Urine and Stool Routine Tests
2.6.Blood Electrolytes Tests
2.7.Coagulation Function Tests
2.8.Serum Liver Function Tests

ALT

11.8 IU/L

AST

15.0 IU/L

2.9.HBV Markers Test
2.10.Renel Function Test

Creatinine

47.8 umol/L

Urea nitrogen

4.67

UA

276.4 mmol/l

2.11.Heat Function Examination
2.12.Blood Cell Morphology
2.13.Image Examinations
2.14.Nervous System Examination
2.15.Lung Function Examination
2.16.Blood Gas Analysis
2.17.Physical Ability Examination
2.18.Health Relative Quality of Life
3.In the process of the treatment
3.1.Treatment Record
4.At the end of the treatment
4.1.Management for Progress
4.2.Physical examination
4.3.Blood Routine Tests
4.4.Urine and Stool Routine Tests
4.5.Serum Electrolytes Tests
4.6.Liver Function Tests
4.7.HBV Markers Test
4.8.Renel Function Test
4.9.Heat Function Examination
4.10.Image Examinations
4.11.Blood Cell Morphology
4.12.Nervous System Examination
4.13.Lung Function Examination
4.14.Blood Gas Analysis
4.15.Physical Sbility Examination
4.16.Health Relative Quality of Life
5.Follow-up 1
1.Blood routine test
6.Follow-up 2
7.Follow-up 3
8.Management system of participants
9.Speciman management system
10.Data management system
11.ADR/ADE management system
12.Madicine management system
13.Instruments management system
14.SOPs
14.1.Treatment SOP
14.2.Nursing SOP
14.3.Specimen collection SOP
15.Research team
15.1.Institutions
15.2.Researchers
16.Design, Methods
16.1.Calculation of sample size