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1.Screening
1.2.Inclusion Criteria

Age over 18

Yes

Yes

Yes

1.3.Exclusion Criteria

No

No

No

No

No

No

2.Baseline

Age

19

Gender

Male

11

0

0

2.8

1

3.In the process of the operation

第五掌骨

施德源

腋路

4.At the end of PACU stay
5.Follow-up8h

0

0

ug

7.1 mmol/L

6.Follow-up12h

0

0

19.2 ug

7.Follow-up24h

0

0

27.6 ug

Negative

1

8.Follow-up48h

0

0

27.6 ug

未觉明显疼痛

5

9.Follow-up30d

NO

10.Data management system
11.ADR/ADE management system

2018.1.25因不痛停泵

12.Madicine management system
13.Instruments management system
14.SOPs
14.1.Treatment SOP
14.2.Nursing SOP
14.3.Specimen collection SOP
15.Research team
15.1.Institutions
15.2.Researchers
16.Design, Methods
16.1.Calculation of sample size