1.Screening
1.1.Number for subjects
02 |
1.2.Inclusion Criteria
Subjects aged 18 to 80 taking enteric coated aspirin for primary prevention of cardiovascular diseases
/Taking enteric coated aspirin for more than 1 month
/Agreeing with the treating plan
/Voluntarily signing the informed consent
|
1.3.Exclusion Criteria
1.4.Researcher
张杰 |
2.Baseline
2.1.Time of entering
2019/07/24 (YYYY/MM/DD) |
2.2.General information
2.2.2.2.2.1、Name
JHB |
2.2.2.2.2.2、Age
62 y |
2.2.2.2.2.3、Height
158 cm |
2.2.2.2.2.4、Weight
68 Kg |
2.2.2.2.2.5、BMI
27.24 Kg/cm2 |
2.2.2.2.2.6、Smoking
无 |
2.2.2.2.2.7、Drinking alcohol
无 |
2.2.2.2.2.8、Disease
Hypertension
/Diabetes mellitus
/Coronary heart disease
/Cerebrovascular disease
|
2.2.2.2.2.9、Aspirin period
12 month |
2.2.2.2.2.10、Other drugs information
胰岛素，硝苯地平 |
3.Data before the treatment
- GSRS
- Gastric injury Lanza score
- Whether there is small intestinal mucosal injury (erosion or ulcer),
- Small intestine injury score
- Whether or not to complete the smll intestine test
- Other results of MCCE
- Gastric examining time
- Small intestine passing time
- Side effect of MCCE
- Capsule passing time
- Serum TNF-α level
- Serum IL-1β level
- Serum IL-10 level
- Serum PGE2 level
- Serum TLR4 level
- Examining time before the treatment
- Other results
3.1.GSRS
7 |
3.2.Gastric injury Lanza score
2 |
3.3.Whether there is small intestinal mucosal injury (erosion or ulcer),
No
|
3.4.Small intestine injury score
1 |
3.5.Whether or not to complete the smll intestine test
Complete
|
3.6.Other results of MCCE
无 |
3.7.Gastric examining time
30 min |
3.8.Small intestine passing time
300 min |
3.9.Side effect of MCCE
无 |
3.10.Capsule passing time
18 hour |
3.11.Serum TNF-α level
36.30 |
3.12.Serum IL-1β level
3.98 |
3.13.Serum IL-10 level
3.42 |
3.14.Serum PGE2 level
245.52 |
3.15.Serum TLR4 level
|
3.16.Examining time before the treatment
2019/07/24 (YYYY/MM/DD) |
3.17.Other results
无 |
4.Information during the treatment
4.1.Whether or not to take medicine regularly
Yes
|
4.2.Whether or not to exit the research or loss of follow-up
Continue
|
5.Data after the treatment
- GSRS after treatmrnt
- Gastric injury Lanza score after treatment
- Whether there is small intestinal mucosal injury (erosion or ulcer) after treatment
- Small intestine injury score after treatment
- Whether or not to complete the smll intestine test after treatment
- Other result of MCCE after treatment
- Gastric examining time after treatment
- Small intestine passing time after treatment
- Side effect of MCCE after treatment
- Capsule passing time after treatment
- Serum TNF-α level after treatment
- Serum IL-1β level after treatment
- Serum IL-10 level after treatment
- Serum PGE2 level after treatment
- Serum TLR4 level after treatment
- Examining time after treatment
- Other results after treatment
- Whether or not to complete the research
- Are there any adverse events during the research?
5.1.GSRS after treatmrnt
5 |
5.2.Gastric injury Lanza score after treatment
1 |
5.3.Whether there is small intestinal mucosal injury (erosion or ulcer) after treatment
No
|
5.4.Small intestine injury score after treatment
1 |
5.5.Whether or not to complete the smll intestine test after treatment
Complete
|
5.6.Other result of MCCE after treatment
黄色瘤 |
5.7.Gastric examining time after treatment
30 min |
5.8.Small intestine passing time after treatment
260 min |
5.9.Side effect of MCCE after treatment
无 |
5.10.Capsule passing time after treatment
22 hour |
5.11.Serum TNF-α level after treatment
41.48 |
5.12.Serum IL-1β level after treatment
6.63 |
5.13.Serum IL-10 level after treatment
3.64 |
5.14.Serum PGE2 level after treatment
89.34 |
5.15.Serum TLR4 level after treatment
|
5.16.Examining time after treatment
2019/08/24 (YYYY/MM/DD) |
5.17.Other results after treatment
|
5.18.Whether or not to complete the research
Complete the research
|
5.19.Are there any adverse events during the research?
无 |