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1.Screening
1.1.Number for subjects

04

1.2.Inclusion Criteria

Subjects aged 18 to 80 taking enteric coated aspirin for primary prevention of cardiovascular diseases
/
Taking enteric coated aspirin for more than 1 month
/
Agreeing with the treating plan
/
Voluntarily signing the informed consent

1.3.Exclusion Criteria

1.4.Researcher

张杰

2.Baseline
2.1.Time of entering

2019/07/27 (YYYY/MM/DD)

2.2.General information
2.2.2.2.2.1、Name

CPL

2.2.2.2.2.2、Age

71 y

2.2.2.2.2.3、Height

175 cm

2.2.2.2.2.4、Weight

85 Kg

2.2.2.2.2.5、BMI

27.75 Kg/cm2

2.2.2.2.2.6、Smoking

2.2.2.2.2.7、Drinking alcohol

2.2.2.2.2.8、Disease

Hypertension
/
Coronary heart disease
/
Hyperlipemia

2.2.2.2.2.9、Aspirin period

48 month

2.2.2.2.2.10、Other drugs information

立普妥

3.Data before the treatment
3.1.GSRS

5

3.2.Gastric injury Lanza score

4

3.3.Whether there is small intestinal mucosal injury (erosion or ulcer),

3.4.Small intestine injury score

4

3.5.Whether or not to complete the smll intestine test

Complete

3.6.Other results of MCCE

3.7.Gastric examining time

30 min

3.8.Small intestine passing time

100 min

3.9.Side effect of MCCE

3.10.Capsule passing time

16 hour

3.11.Serum TNF-α level

387.22

3.12.Serum IL-1β level

10.60

3.13.Serum IL-10 level

17.07

3.14.Serum PGE2 level

70.43

3.15.Serum TLR4 level

3.16.Examining time before the treatment

2019/07/27 (YYYY/MM/DD)

3.17.Other results

4.Information during the treatment
4.1.Whether or not to take medicine regularly

Yes

4.2.Whether or not to exit the research or loss of follow-up

Continue

5.Data after the treatment
5.1.GSRS after treatmrnt

3

5.2.Gastric injury Lanza score after treatment

2

5.3.Whether there is small intestinal mucosal injury (erosion or ulcer) after treatment

Yes

5.4.Small intestine injury score after treatment

2

5.5.Whether or not to complete the smll intestine test after treatment

Complete

5.6.Other result of MCCE after treatment

5.7.Gastric examining time after treatment

30 min

5.8.Small intestine passing time after treatment

120 min

5.9.Side effect of MCCE after treatment

5.10.Capsule passing time after treatment

18 hour

5.11.Serum TNF-α level after treatment

976.67

5.12.Serum IL-1β level after treatment

15.18

5.13.Serum IL-10 level after treatment

20.43

5.14.Serum PGE2 level after treatment

102.96

5.15.Serum TLR4 level after treatment

5.16.Examining time after treatment

2019/08/27 (YYYY/MM/DD)

5.17.Other results after treatment

5.18.Whether or not to complete the research

Complete the research

5.19.Are there any adverse events during the research?