1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years
YES
|
1.1.2.1.2.2、
III |
1.1.2.1.2.3、Heart valve replacement surgery
YES
|
1.3.Exclusion Criteria
|
With at least one disease as listed following | Left ventricular ejection fraction <45%
/Acute Cardiac Failure
/Myocardial Infarction
/History of angina in the past week
/Any coronary stenosis >70%
/Severe brain, kidney, lung, liver disease
/Tropisetron allergy
/Uncontrolled hypertension
|
2.Baseline
2.1.Surgical name
主动脉瓣机械置换术+二尖瓣机械版膜置换术+三尖瓣成形术 |
2.2.Age
64 |
2.3.Gender
Male
|
2.4.BMI
24.9 20.8 |
2.5.Cardiac Function
III |
2.6.Ejection fraction
64 |
2.7.
III |
2.8.LEVDD
60 |
2.9.LAD
54 |
3.Time Data
- CPB Time
- Blocking Time
- Operation Time
- Duration of ventilation
- ICU Standing time
- Postoperation stay in hospital
3.1.CPB Time
160 |
3.2.Blocking Time
140 |
3.3.Operation Time
360 |
3.4.Duration of ventilation
22.5 |
3.5.ICU Standing time
64 |
3.6.Postoperation stay in hospital
18 |
4.Blood pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
4.1.Before anesthesia
94.33 |
4.2.Before extracorporeal circulation
85.67 |
4.3.After extracorporeal circulation
78 |
4.4.4 hours after cardiopulmonary bypass
100.67 |
4.5.12 hours after cardiopulmonary bypass
81.67 |
4.6.24 hours after cardiopulmonary bypass
82 |
5.Heart rate
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
5.1.Before anesthesia
79 |
5.2.Before extracorporeal circulation
91 |
5.3.After extracorporeal circulation
109 |
5.4.4 hours after cardiopulmonary bypass
94 |
5.5.12 hours after cardiopulmonary bypass
96 |
5.6.24 hours after cardiopulmonary bypass
98 |
7.
7.1.
7.7.1.7.1.1、
184.57488 |
7.7.1.7.1.2、
604.91678 |
7.7.1.7.1.3、
458.02218 |
7.7.1.7.1.4、
543.33272 |
7.2.
7.7.2.7.2.1、
11.079864 |
7.7.2.7.2.2、
50.392832 |
7.7.2.7.2.3、
27.878284 |
7.7.2.7.2.4、
18.33817 |
7.3.
7.7.3.7.3.1、
13.175 |
7.7.3.7.3.2、
14.925 |
7.7.3.7.3.3、
13.175 |
7.7.3.7.3.4、
11.925 |
7.4.
7.7.4.7.4.1、
8.543003 |
7.7.4.7.4.2、
8.543003 |
7.7.4.7.4.3、
10.843669 |
7.7.4.7.4.4、
11.374592 |
7.5.
7.7.5.7.5.1、
174.5490982 |
7.7.5.7.5.2、
338.6773547 |
7.7.5.7.5.3、
432.8657315 |
7.7.5.7.5.4、
547.0941884 |
7.6.
7.7.6.7.6.1、
0.09437908 |
7.7.6.7.6.2、
3.071577847 |
7.7.6.7.6.3、
3.792580982 |
7.7.6.7.6.4、
0.501044932 |
7.7.
7.7.7.7.7.1、
6.03 |
7.7.7.7.7.2、
10.44 |
7.8.
7.7.8.7.8.1、
5.3 |
7.7.8.7.8.2、
9.03 |
7.9.
7.7.9.7.9.1、
71 |
7.7.9.7.9.2、
71 |
7.10.
7.7.10.7.10.1、
0.08 |
7.7.10.7.10.2、
99.5 |
6.Central Venous Pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
6.1.Before anesthesia
7 |
6.2.Before extracorporeal circulation
8 |
6.3.After extracorporeal circulation
7 |
6.4.4 hours after cardiopulmonary bypass
7 |
6.5.12hours after cardiopulmonary bypass
8 |
6.6.24 hours after cardiopulmonary bypass
7 |
9.postoperative complications
- Ventricular arrhythmia
- Perioperative MI
- Cerebrovascular accidents
- Abnormal coagulation function
- pulmonary Infection
- Shock
- Endocarditis
- Hospital death
9.1.Ventricular arrhythmia
NO
|
9.2.Perioperative MI
NO
|
9.3.Cerebrovascular accidents
NO
|
9.4.Abnormal coagulation function
YES
|
9.5.pulmonary Infection
NO
|
9.6.Shock
NO
|
9.7.Endocarditis
NO
|
9.8.Hospital death
NO
|