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1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years

YES

1.1.2.1.2.2、

III

1.1.2.1.2.3、Heart valve replacement surgery

YES

1.3.Exclusion Criteria

With at least one disease as listed following

Left ventricular ejection fraction <45%
/
Acute Cardiac Failure
/
Myocardial Infarction
/
History of angina in the past week
/
Any coronary stenosis >70%
/
Severe brain, kidney, lung, liver disease
/
Tropisetron allergy
/
Uncontrolled hypertension

3.Time Data
3.1.CPB Time

85

3.2.Blocking Time

70

3.3.Operation Time

200

3.4.Duration of ventilation

13

3.5.ICU Standing time

42.6

3.6.Postoperation stay in hospital

16

2.Baseline
2.1.Surgical name

二尖瓣机械版膜置换术+三尖瓣成形术

2.2.Age

40

2.3.Gender

female

2.4.BMI

24.77

2.5.Cardiac Function

II

2.6.Ejection fraction

56

2.7.

III

2.8.LEVDD

49

2.9.LAD

41

4.Blood pressure
4.1.Before anesthesia

77.33

4.2.Before extracorporeal circulation

78.66

4.3.After extracorporeal circulation

92

4.4.4 hours after cardiopulmonary bypass

79

4.5.12 hours after cardiopulmonary bypass

77.66

4.6.24 hours after cardiopulmonary bypass

82.33

5.Heart rate
5.1.Before anesthesia

57

5.2.Before extracorporeal circulation

62

5.3.After extracorporeal circulation

71

5.4.4 hours after cardiopulmonary bypass

119

5.5.12 hours after cardiopulmonary bypass

99

5.6.24 hours after cardiopulmonary bypass

103

7.
7.1.
7.7.1.7.1.1、

140.5065

7.7.1.7.1.2、

502.09056

7.7.1.7.1.3、

384.57488

7.7.1.7.1.4、

587.4011

7.2.
7.7.2.7.2.1、

10.706956

7.7.2.7.2.2、

49.078276

7.7.2.7.2.3、

46.517376

7.7.2.7.2.4、

35.775454

7.3.
7.7.3.7.3.1、

10.675

7.7.3.7.3.2、

8.675

7.7.3.7.3.3、

10.425

7.7.3.7.3.4、

13.175

7.4.
7.7.4.7.4.1、

10.312746

7.7.4.7.4.2、

12.08249

7.7.4.7.4.3、

10.666695

7.7.4.7.4.4、

10.843669

7.5.
7.7.5.7.5.1、

188.3767535

7.7.5.7.5.2、

490.9819639

7.7.5.7.5.3、

422.8456914

7.7.5.7.5.4、

398.7975952

7.6.
7.7.6.7.6.1、

0.030825496

7.7.6.7.6.2、

7.146812957

7.7.6.7.6.3、

1.566875653

7.7.6.7.6.4、

1.739289446

7.7.
7.7.7.7.7.1、

5.94

7.7.7.7.7.2、

16.8

7.8.
7.7.8.7.8.1、

3.54

7.7.8.7.8.2、

15.38

7.9.
7.7.9.7.9.1、

187

7.7.9.7.9.2、

95

7.10.
7.7.10.7.10.1、

1.79

7.7.10.7.10.2、

193.6

6.Central Venous Pressure
6.1.Before anesthesia

10

6.2.Before extracorporeal circulation

10

6.3.After extracorporeal circulation

12

6.4.4 hours after cardiopulmonary bypass

9

6.5.12hours after cardiopulmonary bypass

10

6.6.24 hours after cardiopulmonary bypass

15

9.postoperative complications
9.1.Ventricular arrhythmia

NO

9.2.Perioperative MI

NO

9.3.Cerebrovascular accidents

NO

9.4.Abnormal coagulation function

NO

9.5.pulmonary Infection

NO

9.6.Shock

NO

9.7.Endocarditis

NO

9.8.Hospital death

NO