1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years
YES
|
1.1.2.1.2.2、
II |
1.1.2.1.2.3、Heart valve replacement surgery
YES
|
1.3.Exclusion Criteria
|
With at least one disease as listed following | Left ventricular ejection fraction <45%
/Acute Cardiac Failure
/Myocardial Infarction
/History of angina in the past week
/Any coronary stenosis >70%
/Severe brain, kidney, lung, liver disease
/Tropisetron allergy
/Uncontrolled hypertension
|
2.Baseline
2.1.Surgical name
主动脉瓣机械置换术+房室间隔修补术 |
2.2.Age
31 |
2.3.Gender
Male
|
2.4.BMI
22.49134948 |
2.5.Cardiac Function
III |
2.6.Ejection fraction
58 |
2.7.
II |
2.8.LEVDD
42 |
2.9.LAD
32 |
3.Time Data
- CPB Time
- Blocking Time
- Operation Time
- Duration of ventilation
- ICU Standing time
- Postoperation stay in hospital
3.1.CPB Time
90 |
3.2.Blocking Time
50 |
3.3.Operation Time
200 |
3.4.Duration of ventilation
23 |
3.5.ICU Standing time
43.5 |
3.6.Postoperation stay in hospital
11 |
4.Blood pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
4.1.Before anesthesia
91 |
4.2.Before extracorporeal circulation
90 |
4.3.After extracorporeal circulation
84.33 |
4.4.4 hours after cardiopulmonary bypass
72.67 |
4.5.12 hours after cardiopulmonary bypass
71.33 |
4.6.24 hours after cardiopulmonary bypass
77.33 |
5.Heart rate
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
5.1.Before anesthesia
90 |
5.2.Before extracorporeal circulation
70 |
5.3.After extracorporeal circulation
89 |
5.4.4 hours after cardiopulmonary bypass
97 |
5.5.12 hours after cardiopulmonary bypass
94 |
5.6.24 hours after cardiopulmonary bypass
103 |
7.
7.1.
7.7.1.7.1.1、
146.15894 |
7.7.1.7.1.2、
634.2957 |
7.7.1.7.1.3、
1075.53786 |
7.7.1.7.1.4、
719.60624 |
7.2.
7.7.2.7.2.1、
11.575062 |
7.7.2.7.2.2、
72.421848 |
7.7.2.7.2.3、
56.002842 |
7.7.2.7.2.4、
45.495776 |
7.3.
7.7.3.7.3.1、
31.675 |
7.7.3.7.3.2、
38.175 |
7.7.3.7.3.3、
37.425 |
7.7.3.7.3.4、
41.425 |
7.4.
7.7.4.7.4.1、
15.62289596 |
7.7.4.7.4.2、
21.48148182 |
7.7.4.7.4.3、
11.88552222 |
7.7.4.7.4.4、
26.93602727 |
7.5.
7.7.5.7.5.1、
152.50501 |
7.7.5.7.5.2、
430.8617235 |
7.7.5.7.5.3、
272.5450902 |
7.7.5.7.5.4、
470.5410822 |
7.6.
7.7.6.7.6.1、
0.161442006 |
7.7.6.7.6.2、
0.271159875 |
7.7.6.7.6.3、
0.271151.556426332 |
7.7.6.7.6.4、
0.020376176 |
7.7.
7.7.7.7.7.1、
2.89 |
7.7.7.7.7.2、
15.34 |
7.8.
7.7.8.7.8.1、
3.67 |
7.7.8.7.8.2、
10.51 |
7.9.
7.7.9.7.9.1、
206 |
7.7.9.7.9.2、
217 |
7.10.
7.7.10.7.10.1、
1.62 |
7.7.10.7.10.2、
133.7 |
6.Central Venous Pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
6.1.Before anesthesia
7 |
6.2.Before extracorporeal circulation
8 |
6.3.After extracorporeal circulation
10 |
6.4.4 hours after cardiopulmonary bypass
12 |
6.5.12hours after cardiopulmonary bypass
12 |
6.6.24 hours after cardiopulmonary bypass
12 |
9.postoperative complications
- Ventricular arrhythmia
- Perioperative MI
- Cerebrovascular accidents
- Abnormal coagulation function
- pulmonary Infection
- Shock
- Endocarditis
- Hospital death
9.1.Ventricular arrhythmia
NO
|
9.2.Perioperative MI
NO
|
9.3.Cerebrovascular accidents
NO
|
9.4.Abnormal coagulation function
NO
|
9.5.pulmonary Infection
NO
|
9.6.Shock
NO
|
9.7.Endocarditis
NO
|
9.8.Hospital death
NO
|