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1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years

YES

1.1.2.1.2.2、

II

1.1.2.1.2.3、Heart valve replacement surgery

YES

1.3.Exclusion Criteria

With at least one disease as listed following

Left ventricular ejection fraction <45%
/
Acute Cardiac Failure
/
Myocardial Infarction
/
History of angina in the past week
/
Any coronary stenosis >70%
/
Severe brain, kidney, lung, liver disease
/
Tropisetron allergy
/
Uncontrolled hypertension

2.Baseline
2.1.Surgical name

主动脉瓣机械置换术

2.2.Age

36

2.3.Gender

Male

2.4.BMI

25.0995016

2.5.Cardiac Function

III

2.6.Ejection fraction

63

2.7.

III

2.8.LEVDD

58

2.9.LAD

31

3.Time Data
3.1.CPB Time

125

3.2.Blocking Time

55

3.3.Operation Time

295

3.4.Duration of ventilation

11

3.5.ICU Standing time

41.33

3.6.Postoperation stay in hospital

15

4.Blood pressure
4.1.Before anesthesia

98

4.2.Before extracorporeal circulation

82.67

4.3.After extracorporeal circulation

80

4.4.4 hours after cardiopulmonary bypass

86.33

4.5.12 hours after cardiopulmonary bypass

89.33

4.6.24 hours after cardiopulmonary bypass

92.67

5.Heart rate
5.1.Before anesthesia

88

5.2.Before extracorporeal circulation

93

5.3.After extracorporeal circulation

100

5.4.4 hours after cardiopulmonary bypass

85

5.5.12 hours after cardiopulmonary bypass

95

5.6.24 hours after cardiopulmonary bypass

103

7.
7.1.
7.7.1.7.1.1、

160.8484

7.7.1.7.1.2、

839.94814

7.7.1.7.1.3、

1693.05354

7.7.1.7.1.4、

778.36408

7.2.
7.7.2.7.2.1、

10.831404

7.7.2.7.2.2、

158.908928

7.7.2.7.2.3、

139.401396

7.7.2.7.2.4、

84.96973

7.3.
7.7.3.7.3.1、

28.925

7.7.3.7.3.2、

83.175

7.7.3.7.3.3、

50.425

7.7.3.7.3.4、

46.925

7.4.
7.7.4.7.4.1、

1.885522222

7.7.4.7.4.2、

4.915825253

7.7.4.7.4.3、

3.097643434

7.7.4.7.4.4、

9.764310101

7.5.
7.7.5.7.5.1、

124.248497

7.7.5.7.5.2、

416.8336673

7.7.5.7.5.3、

330.6613227

7.7.5.7.5.4、

428.6573146

7.6.
7.7.6.7.6.1、

0.725705329

7.7.6.7.6.2、

14.17398119

7.7.6.7.6.3、

3.390282132

7.7.6.7.6.4、

2.308777429

7.7.
7.7.7.7.7.1、

4.65

7.7.7.7.7.2、

11.95

7.8.
7.7.8.7.8.1、

3.69

7.7.8.7.8.2、

13.47

7.9.
7.7.9.7.9.1、

197

7.7.9.7.9.2、

129

7.10.
7.7.10.7.10.1、

0.41

7.7.10.7.10.2、

519.73

6.Central Venous Pressure
6.1.Before anesthesia

6

6.2.Before extracorporeal circulation

6

6.3.After extracorporeal circulation

5

6.4.4 hours after cardiopulmonary bypass

6

6.5.12hours after cardiopulmonary bypass

7

6.6.24 hours after cardiopulmonary bypass

9

9.postoperative complications
9.1.Ventricular arrhythmia

YES

9.2.Perioperative MI

NO

9.3.Cerebrovascular accidents

NO

9.4.Abnormal coagulation function

NO

9.5.pulmonary Infection

NO

9.6.Shock

NO

9.7.Endocarditis

NO

9.8.Hospital death

NO