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1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years

YES

1.1.2.1.2.2、

III

1.1.2.1.2.3、Heart valve replacement surgery

YES

1.3.Exclusion Criteria

With at least one disease as listed following

Left ventricular ejection fraction <45%
/
Acute Cardiac Failure
/
Myocardial Infarction
/
History of angina in the past week
/
Any coronary stenosis >70%
/
Severe brain, kidney, lung, liver disease
/
Tropisetron allergy
/
Uncontrolled hypertension

3.Time Data
3.1.CPB Time

235

3.2.Blocking Time

135

3.3.Operation Time

525

3.4.Duration of ventilation

24

3.5.ICU Standing time

37.5

3.6.Postoperation stay in hospital

16

2.Baseline
2.1.Surgical name

二尖瓣机械版膜置换术+三尖瓣探查术

2.2.Age

53

2.3.Gender

female

2.4.BMI

29.38

2.5.Cardiac Function

II

2.6.Ejection fraction

63

2.7.

III

2.8.LEVDD

52

2.9.LAD

46

4.Blood pressure
4.1.Before anesthesia

89.33

4.2.Before extracorporeal circulation

73

4.3.After extracorporeal circulation

78

4.4.4 hours after cardiopulmonary bypass

78.66

4.5.12 hours after cardiopulmonary bypass

72.67

4.6.24 hours after cardiopulmonary bypass

96.5

5.Heart rate
5.1.Before anesthesia

77

5.2.Before extracorporeal circulation

92

5.3.After extracorporeal circulation

102

5.4.4 hours after cardiopulmonary bypass

107

5.5.12 hours after cardiopulmonary bypass

100

5.6.24 hours after cardiopulmonary bypass

101

7.
7.1.
7.7.1.7.1.1、

325.81704

7.7.1.7.1.2、

1221.8741

7.7.1.7.1.3、

1534.2957

7.7.1.7.1.4、

704.91678

7.2.
7.7.2.7.2.1、

5.94497

7.7.2.7.2.2、

31.785058

7.7.2.7.2.3、

25.057554

7.7.2.7.2.4、

25.457444

7.3.
7.7.3.7.3.1、

16.675

7.7.3.7.3.2、

15.175

7.7.3.7.3.3、

12.675

7.7.3.7.3.4、

20.925

7.4.
7.7.4.7.4.1、

7.922642

7.7.4.7.4.2、

10.312746

7.7.4.7.4.3、

8.099617

7.7.4.7.4.4、

12.790387

7.5.
7.7.5.7.5.1、

212.6252505

7.7.5.7.5.2、

645.2905812

7.7.5.7.5.3、

507.0140281

7.7.5.7.5.4、

462.9258517

7.6.
7.7.6.7.6.1、

0.532392894

7.7.6.7.6.2、

4.581504702

7.7.6.7.6.3、

1.26907001

7.7.6.7.6.4、

0.939916405

7.7.
7.7.7.7.7.1、

5.58

7.7.7.7.7.2、

12.28

7.8.
7.7.8.7.8.1、

3.3

7.7.8.7.8.2、

10.98

7.9.
7.7.9.7.9.1、

245

7.7.9.7.9.2、

148

7.10.
7.7.10.7.10.1、

0.7

7.7.10.7.10.2、

117

6.Central Venous Pressure
6.1.Before anesthesia

9

6.2.Before extracorporeal circulation

9

6.3.After extracorporeal circulation

12

6.4.4 hours after cardiopulmonary bypass

17

6.5.12hours after cardiopulmonary bypass

14

6.6.24 hours after cardiopulmonary bypass

15

9.postoperative complications
9.1.Ventricular arrhythmia

YES

9.2.Perioperative MI

NO

9.3.Cerebrovascular accidents

NO

9.4.Abnormal coagulation function

NO

9.5.pulmonary Infection

YES

9.6.Shock

NO

9.7.Endocarditis

NO

9.8.Hospital death

NO