1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years
YES
|
1.1.2.1.2.2、
III |
1.1.2.1.2.3、Heart valve replacement surgery
YES
|
1.3.Exclusion Criteria
|
With at least one disease as listed following | Left ventricular ejection fraction <45%
/Acute Cardiac Failure
/Myocardial Infarction
/History of angina in the past week
/Any coronary stenosis >70%
/Severe brain, kidney, lung, liver disease
/Tropisetron allergy
/Uncontrolled hypertension
|
2.Baseline
2.1.Surgical name
主动脉瓣机械瓣膜置换术 |
2.2.Age
40 |
2.3.Gender
Male
|
2.4.BMI
25.95 |
2.5.Cardiac Function
III |
2.6.Ejection fraction
56 |
2.7.
III |
2.8.LEVDD
39 |
2.9.LAD
29 |
3.Time Data
- CPB Time
- Blocking Time
- Operation Time
- Duration of ventilation
- ICU Standing time
- Postoperation stay in hospital
3.1.CPB Time
130 |
3.2.Blocking Time
90 |
3.3.Operation Time
285 |
3.4.Duration of ventilation
16 |
3.5.ICU Standing time
37.33 |
3.6.Postoperation stay in hospital
9 |
4.Blood pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
4.1.Before anesthesia
94 |
4.2.Before extracorporeal circulation
71.33 |
4.3.After extracorporeal circulation
67.33 |
4.4.4 hours after cardiopulmonary bypass
76.67 |
4.5.12 hours after cardiopulmonary bypass
74.33 |
4.6.24 hours after cardiopulmonary bypass
98.33 |
5.Heart rate
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
5.1.Before anesthesia
98 |
5.2.Before extracorporeal circulation
89 |
5.3.After extracorporeal circulation
92 |
5.4.4 hours after cardiopulmonary bypass
104 |
5.5.12 hours after cardiopulmonary bypass
106 |
5.6.24 hours after cardiopulmonary bypass
103 |
7.
7.1.
7.7.1.7.1.1、
102.09056 |
7.7.1.7.1.2、
619.60624 |
7.7.1.7.1.3、
531.46948 |
7.7.1.7.1.4、
572.71164 |
7.2.
7.7.2.7.2.1、
7.55868 |
7.7.2.7.2.2、
34.155066 |
7.7.2.7.2.3、
47.527626 |
7.7.2.7.2.4、
25.513498 |
7.3.
7.7.3.7.3.1、
8.175 |
7.7.3.7.3.2、
9.175 |
7.7.3.7.3.3、
10.925 |
7.7.3.7.3.4、
34.675 |
7.4.
7.7.4.7.4.1、
3.144336 |
7.7.4.7.4.2、
17.037771 |
7.7.4.7.4.3、
10.577257 |
7.7.4.7.4.4、
14.914079 |
7.5.
7.7.5.7.5.1、
230.4609218 |
7.7.5.7.5.2、
346.6933868 |
7.7.5.7.5.3、
693.3867735 |
7.7.5.7.5.4、
424.8496994 |
7.6.
7.7.6.7.6.1、
0.124869383 |
7.7.6.7.6.2、
4.957680251 |
7.7.6.7.6.3、
1.509404389 |
7.7.6.7.6.4、
1.608672936 |
7.7.
7.7.7.7.7.1、
7.1 |
7.7.7.7.7.2、
20.38 |
7.8.
7.7.8.7.8.1、
4.42 |
7.7.8.7.8.2、
19.04 |
7.9.
7.7.9.7.9.1、
202 |
7.7.9.7.9.2、
159 |
7.10.
7.7.10.7.10.1、
0.83 |
7.7.10.7.10.2、
155.47 |
6.Central Venous Pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
6.1.Before anesthesia
5 |
6.2.Before extracorporeal circulation
5 |
6.3.After extracorporeal circulation
11 |
6.4.4 hours after cardiopulmonary bypass
9 |
6.5.12hours after cardiopulmonary bypass
10 |
6.6.24 hours after cardiopulmonary bypass
10 |
9.postoperative complications
- Ventricular arrhythmia
- Perioperative MI
- Cerebrovascular accidents
- Abnormal coagulation function
- pulmonary Infection
- Shock
- Endocarditis
- Hospital death
9.1.Ventricular arrhythmia
NO
|
9.2.Perioperative MI
NO
|
9.3.Cerebrovascular accidents
NO
|
9.4.Abnormal coagulation function
NO
|
9.5.pulmonary Infection
YES
|
9.6.Shock
NO
|
9.7.Endocarditis
NO
|
9.8.Hospital death
NO
|