1.Screening
1.2.Inclusion Criteria
1.1.2.1.2.1、Age30~70years
YES
|
1.1.2.1.2.2、
III |
1.1.2.1.2.3、Heart valve replacement surgery
YES
|
1.3.Exclusion Criteria
|
With at least one disease as listed following | Left ventricular ejection fraction <45%
/Acute Cardiac Failure
/Myocardial Infarction
/History of angina in the past week
/Any coronary stenosis >70%
/Severe brain, kidney, lung, liver disease
/Tropisetron allergy
/Uncontrolled hypertension
|
2.Baseline
2.1.Surgical name
二尖瓣置换术+主动脉探查术+三尖瓣成形术 |
2.2.Age
47 |
2.3.Gender
Male
|
2.4.BMI
20.2 |
2.5.Cardiac Function
III |
2.6.Ejection fraction
52 |
2.7.
III |
2.8.LEVDD
52 |
2.9.LAD
46 |
3.Time Data
- CPB Time
- Blocking Time
- Operation Time
- Duration of ventilation
- ICU Standing time
- Postoperation stay in hospital
3.1.CPB Time
80 |
3.2.Blocking Time
50 |
3.3.Operation Time
230 |
3.4.Duration of ventilation
21 |
3.5.ICU Standing time
66.5 |
3.6.Postoperation stay in hospital
18 |
4.Blood pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
4.1.Before anesthesia
89.67 |
4.2.Before extracorporeal circulation
73.33 |
4.3.After extracorporeal circulation
67.33 |
4.4.4 hours after cardiopulmonary bypass
80.33 |
4.5.12 hours after cardiopulmonary bypass
82 |
4.6.24 hours after cardiopulmonary bypass
91.66 |
5.Heart rate
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12 hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
5.1.Before anesthesia
102 |
5.2.Before extracorporeal circulation
88 |
5.3.After extracorporeal circulation
95 |
5.4.4 hours after cardiopulmonary bypass
101 |
5.5.12 hours after cardiopulmonary bypass
111 |
5.6.24 hours after cardiopulmonary bypass
105 |
7.
7.1.
7.7.1.7.1.1、
257.46382 |
7.7.1.7.1.2、
972.15328 |
7.7.1.7.1.3、
1084.01652 |
7.7.1.7.1.4、
563.11626 |
7.2.
7.7.2.7.2.1、
10.69561 |
7.7.2.7.2.2、
90.751918 |
7.7.2.7.2.3、
31.199674 |
7.7.2.7.2.4、
41.576942 |
7.3.
7.7.3.7.3.1、
10.425 |
7.7.3.7.3.2、
11.425 |
7.7.3.7.3.3、
11.175 |
7.7.3.7.3.4、
25.425 |
7.4.
7.7.4.7.4.1、
5.975925 |
7.7.4.7.4.2、
15.975925 |
7.7.4.7.4.3、
12.329874 |
7.7.4.7.4.4、
16.860796 |
7.5.
7.7.5.7.5.1、
132.2645291 |
7.7.5.7.5.2、
623.246493 |
7.7.5.7.5.3、
310.6212425 |
7.7.5.7.5.4、
374.749499 |
7.6.
7.7.6.7.6.1、
0.096656217 |
7.7.6.7.6.2、
6.700626959 |
7.7.6.7.6.3、
3.735109718 |
7.7.6.7.6.4、
2.564785789 |
7.7.
7.7.7.7.7.1、
8.18 |
7.7.7.7.7.2、
20.39 |
7.8.
7.7.8.7.8.1、
4.36 |
7.7.8.7.8.2、
17.93 |
7.9.
7.7.9.7.9.1、
187 |
7.7.9.7.9.2、
215 |
7.10.
7.7.10.7.10.1、
0.63 |
7.7.10.7.10.2、
123 |
6.Central Venous Pressure
- Before anesthesia
- Before extracorporeal circulation
- After extracorporeal circulation
- 4 hours after cardiopulmonary bypass
- 12hours after cardiopulmonary bypass
- 24 hours after cardiopulmonary bypass
6.1.Before anesthesia
6 |
6.2.Before extracorporeal circulation
7 |
6.3.After extracorporeal circulation
8 |
6.4.4 hours after cardiopulmonary bypass
6 |
6.5.12hours after cardiopulmonary bypass
8 |
6.6.24 hours after cardiopulmonary bypass
10 |
9.postoperative complications
- Ventricular arrhythmia
- Perioperative MI
- Cerebrovascular accidents
- Abnormal coagulation function
- pulmonary Infection
- Shock
- Endocarditis
- Hospital death
9.1.Ventricular arrhythmia
NO
|
9.2.Perioperative MI
NO
|
9.3.Cerebrovascular accidents
NO
|
9.4.Abnormal coagulation function
NO
|
9.5.pulmonary Infection
NO
|
9.6.Shock
NO
|
9.7.Endocarditis
NO
|
9.8.Hospital death
NO
|