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1.Screening
1.1.inclusion criteria

inclusion criteria

Patients with hyperthyroidism as the chief complaint

1.2.exclusion criteria

Patients with one of the following exclusion criteria

1.3.doctor name

doctor name

熊周怡

2.Baseline
2.1.General information

patient name

曾雯旎

birthday

1994-04-30

gender

female

nation

Han

ABO blood type

unidentified

RH blood type

unidentified

certificate type

identity card

ID number

440204199404303040

place of residence

广东省韶关市浈江区

marital status

married

Highest Education Level

undergraduate college

occupation

managemant

medical insurance

Basic medical insurance for urban workers

name of contact

phone

2.2.Medical information
2.2.2.2.2.1、first

content

outpatient

hospital name

粤北人民医院

register number

03756187

date of hospital visiting

2022-09-10

department

内分泌科

current diagnose

Graves病

Consistent with the final diagnosis

yes

2.2.2.2.2.2、second

content

hospital name

register number

date of hospital visiting

department

current diagnose

Consistent with the final diagnosis

2.2.2.2.2.3、third

content

hospital name

register number

就诊日期/住院日期

department

current diagnose

Consistent with the final diagnosis

2.2.2.2.2.4、fourth

content

hospital name

register number

date of hospital visiting

department

current diagnose

Consistent with the final diagnosis

2.2.2.2.2.5、onset situation

Whether the first visiting

yes

onset season

summer

recurrent

no

Time of first attack

2.3.Relevant medication status before treatment
2.2.3.2.3.1、Whether the drug use

whether the drug

2.2.3.2.3.2、drug1

drug name

doseage

unit of doseage

administration route

Dosing frequency

start date

time of duration(days)

2.2.3.2.3.3、drug2

drug name

doseage

unit of doseage

administration route

Dosing frequency

start date

time of duration(days)

2.2.3.2.3.4、drug3

drug name

doseage

unit of doseage

administration route

Dosing frequency

start date

time of duration(days)

2.4.Physical examination

Vital signs and laboratory examination

Yes

date

2022-09-10

2.2.4.2.4.2、system

overall appearance

normal

EENT

normal

head

normal

lung

normal

abdoman

normal

Spinal&limbs

normal

2.2.4.2.4.4、vital signs

height(cm)

160

weight(kg)

46

BMI(KG/M2)

17.97

waistline(cm)

body temperature(°C)

36.5

pulse(bpm)

90

heart rate(bpm)

90

breathe(bpm)

20

diastolic pressure(mmHg)

70

systolic pressure(mmHg)

130

2.2.4.2.4.5、thyroid pain

degree

none

location

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.6、fever

time of duration(days)

Whether it is the first symptom

degree

no

2.2.4.2.4.7、cold before onset

yes/no

no

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.8、radiation pain

yes/no

no

location

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.9、paopitation

yes/no

yes

time of duration(days)

30

Whether it is the first symptom

yes

2.2.4.2.4.10、tremble

yes/no

no

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.11、weight lose

yes/no

yes

time of duration(days)

30

Whether it is the first symptom

no

2.2.4.2.4.12、goiter

yes/no

none

location

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.13、thyroid tenderness

yes/no

none

location

time of duration(days)

Whether it is the first symptom

2.5.allergic history

yes/no

allergen

2.6.Relevant Family History

Type of Family Medical History

kinship

2.7.Personal medical history and past history

if has hypertension

if has diabetes

if has coronary heart disease

2.8.laboratory examination
2.2.8.2.8.1、blood routine

WBC

4.39 ×109 /L

NEUT%

55 %

LY%

%

MONO%

RBC

×10^12 /L

HGB

g/L

PLT

×10^9 /L

Researcher signature

熊周怡

Date

2022-09-10 yyyy-mm-dd

2.2.8.2.8.2、Inflammatory biomarkers

ESR(mm/h)

15

C-reaction protein(Mg/ml)

2.2.8.2.8.3、thyroid function

Thyroid stimulating hormone, TSH

<0.005 uIU/ml

FT3

42.3 pmol/L

FT4

>100 pmol/L

Anti-TG

IU/ml

Anti-TP0

IU/ml

Diagnosed as

Hyperthyroidism

2.2.8.2.8.4、thyroid antibody

TRAb(IU/L)

21.72

2.9.影像学检查
2.2.9.2.9.1、thyroid ECT

Thyroid morphology

anthorisma

Taken technetium function

increase

description

甲状腺弥漫性肿大,摄锝功能增加

2.2.9.2.9.2、thyroid B-type ultrasound

thyroid enlargement

none

left lobe width(mm)

19

left lobe thickness

16

right lobe width(mm)

20

right lobe thickness(mm)

16

isthmus thickness(mm)

3

echo

echo thickening

Blood flow situation

Increased blood flow

decribe

甲状腺实质弥漫性病变,请结合临床及实验室检查

2.10.FNAC

Based site

pathology results

description

2.11.diagnostic scale

Thyroid tenderness(6 scores)

no

Firm on palpation(3 scores)

no

Increased ESR(3 scores)

no

elevated thyroid hormone level(2 scores)

yes

total score

2

3.SOPs
3.1.Treatment SOP
3.2.
3.3.Data management system
3.4.ADR/ADE management system
4.Research team
4.1.institutions
4.2.researchers
5.Design, Methods
5.1.Calculation of sample size
6.Management for Progress

Whether got the informed consent?

Date of sign the informed consent

xx年xx月xx日