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1.Screening
1.1.inclusion criteria

inclusion criteria

Patients with hyperthyroidism as the chief complaint

1.2.exclusion criteria

Patients with one of the following exclusion criteria

1.3.doctor name

doctor name

熊周怡

2.Baseline
2.1.General information

patient name

梁建权

birthday

1976-12-22

gender

male

nation

Han

ABO blood type

B type

RH blood type

unidentified

certificate type

identity card

ID number

440203197612221810

place of residence

广东省韶关市武江区

marital status

married

Highest Education Level

undergraduate college

occupation

worker
/
farmer

medical insurance

Basic medical insurance for urban workers

name of contact

phone

2.2.Medical information
2.2.2.2.2.1、first

content

inpatient

hospital name

粤北人民医院

register number

01796837

date of hospital visiting

2023-02-02

department

呼吸内科

current diagnose

发热

Consistent with the final diagnosis

no

2.2.2.2.2.2、second

content

inpatient

hospital name

粤北人民医院

register number

01796837

date of hospital visiting

2023-02-06

department

内分泌科

current diagnose

亚急性甲状腺炎

Consistent with the final diagnosis

yes

2.2.2.2.2.3、third

content

hospital name

register number

就诊日期/住院日期

department

current diagnose

Consistent with the final diagnosis

2.2.2.2.2.4、fourth

content

hospital name

register number

date of hospital visiting

department

current diagnose

Consistent with the final diagnosis

2.2.2.2.2.5、onset situation

Whether the first visiting

no

onset season

winter

recurrent

no

Time of first attack

2.3.Relevant medication status before treatment
2.2.3.2.3.1、Whether the drug use

whether the drug

2.2.3.2.3.2、drug1

drug name

先锋

doseage

表现

unit of doseage

pill

administration route

po

Dosing frequency

other

start date

time of duration(days)

3

2.2.3.2.3.3、drug2

drug name

感冒药

doseage

不详

unit of doseage

administration route

Dosing frequency

start date

time of duration(days)

2.2.3.2.3.4、drug3

drug name

doseage

unit of doseage

administration route

Dosing frequency

start date

time of duration(days)

2.4.Physical examination

Vital signs and laboratory examination

Yes

date

2023-02-02

2.2.4.2.4.2、system

overall appearance

normal

EENT

normal

head

normal

lung

normal

abdoman

normal

Spinal&limbs

normal

2.2.4.2.4.4、vital signs

height(cm)

173

weight(kg)

56

BMI(KG/M2)

18.71

waistline(cm)

body temperature(°C)

36.7

pulse(bpm)

90

heart rate(bpm)

90

breathe(bpm)

20

diastolic pressure(mmHg)

76

systolic pressure(mmHg)

115

2.2.4.2.4.5、thyroid pain

degree

mild

location

both side

time of duration(days)

4

Whether it is the first symptom

no

2.2.4.2.4.6、fever

time of duration(days)

30

Whether it is the first symptom

yes

degree

Moderate fever

2.2.4.2.4.7、cold before onset

yes/no

yes

time of duration(days)

3

Whether it is the first symptom

yes

2.2.4.2.4.8、radiation pain

yes/no

no

location

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.9、paopitation

yes/no

no

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.10、tremble

yes/no

no

time of duration(days)

Whether it is the first symptom

2.2.4.2.4.11、weight lose

yes/no

yes

time of duration(days)

30

Whether it is the first symptom

no

2.2.4.2.4.12、goiter

yes/no

medium

location

both side

time of duration(days)

30

Whether it is the first symptom

no

2.2.4.2.4.13、thyroid tenderness

yes/no

none

location

time of duration(days)

Whether it is the first symptom

2.5.allergic history

yes/no

allergen

2.6.Relevant Family History

Type of Family Medical History

kinship

2.7.Personal medical history and past history

if has hypertension

if has diabetes

if has coronary heart disease

2.8.laboratory examination
2.2.8.2.8.1、blood routine

WBC

7.16 ×109 /L

NEUT%

70.3 %

LY%

%

MONO%

RBC

×10^12 /L

HGB

g/L

PLT

×10^9 /L

Researcher signature

熊周怡

Date

2023-02-05 yyyy-mm-dd

2.2.8.2.8.2、Inflammatory biomarkers

ESR(mm/h)

116

C-reaction protein(Mg/ml)

23.12

2.2.8.2.8.3、thyroid function

Thyroid stimulating hormone, TSH

<0.005 uIU/ml

FT3

15.55 pmol/L

FT4

76.88 pmol/L

Anti-TG

256.04 IU/ml

Anti-TP0

<2 IU/ml

Diagnosed as

Hyperthyroidism

2.2.8.2.8.4、thyroid antibody

TRAb(IU/L)

0.9

2.9.影像学检查
2.2.9.2.9.1、thyroid ECT

Thyroid morphology

unclear

Taken technetium function

decrease

description

甲状腺显影不清,摄锝功能减低

2.2.9.2.9.2、thyroid B-type ultrasound

thyroid enlargement

isthmus

left lobe width(mm)

24

left lobe thickness

22

right lobe width(mm)

24

right lobe thickness(mm)

21

isthmus thickness(mm)

4.9

echo

Echo weakened

Blood flow situation

Increased blood flow

decribe

甲状腺实质弥漫性病变,请结合临床及实验室检查

2.10.FNAC

Based site

pathology results

description

2.11.diagnostic scale

Thyroid tenderness(6 scores)

no

Firm on palpation(3 scores)

yes

Increased ESR(3 scores)

yes

elevated thyroid hormone level(2 scores)

yes

total score

8

3.SOPs
3.1.Treatment SOP
3.2.
3.3.Data management system
3.4.ADR/ADE management system
4.Research team
4.1.institutions
4.2.researchers
5.Design, Methods
5.1.Calculation of sample size
6.Management for Progress

Whether got the informed consent?

Date of sign the informed consent

xx年xx月xx日