- Screening
- Preoperative indications
- Intraoperative indications
- Follow-up one week after aspiration
- Adverse events
- Follow-up 2
- Follow-up 3
- Management system of participants
- Speciman management system
- Data management system
- ADR/ADE management system
- Madicine management system
- Instruments management system
- SOPs
- Research team
- Design, Methods
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Informed consent | Yes
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nodule with high insufficient rate | high cystic nodule
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US assessment accords with FNA criteria recommended by C-TIRADS | Yes
/No
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Thyroid US indicates thyroid nodule. | Yes
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Age ≥ 18 years old | Yes
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Allergic to lidocaine or SonoVue | No
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Patients unable to cooperate for FNA or CEUS | No
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Active infectious focus on cervical skin | No
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Pregnancy | No
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Severe abnormality of coagulation function | No
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Severe abnormality of heart function or lung function | No
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Refuse to CEUS | No
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Date for signing informed consent | 2023-05-12 |
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Telephone | - |
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Sex | Female
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Birthday | - |
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Registration number | 0001067698 |
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Solid component (%) |
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Upper and lower diameter | mm |
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Anteroposterior diameter | mm |
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Coagulation function | |
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transverse diameter | mm |
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Routine blood test | |
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Location of target thyroid nodule | |
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VCs function evaluated by TLUSG | |
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Ultrasonic diagnose |
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Rank of C-TIRADS |
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Score of C-TIRADS |
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Rank of ACR TI-RADS |
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Score of ACR TI-RADS |
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Solid component of sheet-like strong echo (%) |
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Strong echo within nodule | |
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acoustic halo | |
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border | |
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edge | |
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echo |
- Time of aspiration
- Contrast-enhance indication (CEUS-FNA group)
- Progression of operation
- Intraoperative instant complication
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Start time |
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Date of aspiration |
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End time |
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Injection of SonoVue during FNA | |
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Ratio of enhancement |
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No enhancement | |
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Dosage of SonoVue |
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Quality of nodule | |
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Pressure | ml |
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Use of negative pressure | |
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Aspiration times |
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FNA approach | |
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Aspiration needle | |
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Patient compliance | |
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Dosage of local anaesthesics | ml |
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other local anaesthesics |
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Local anesthesia | |
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Machine | |
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Sample capacity | |
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Grittiness |
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visible hemorrhage by CDFI 30 minutes after FNA | |
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methods | |
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extend of hematoma (once after FNA) |
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visible for bleeding by CDFI | |
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location | |
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Aspiration related acute hypersensitivity reaction | |
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Horner syndrome | |
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Vagal nerve syndrome | |
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Voice change | |
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Haemorrhage | |
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Painful when leave interventional room | |
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Analgesic | |
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whether the voice recovers when the patient leaves | |
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VAS score |
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methods | |
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Painful | |
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vocal cord mobility assessment by ultrasound | |
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Allergic to contrast agent | |
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appearance | |
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extend of hematoma (before patient departure) |
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Cytopathology classification | |
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Number of observable follicular epithelial cell clusters in specimen | |
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Whether sample capacity is enough | |
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Pathological number |
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