- Screening
- Preoperative indications
- Intraoperative indications
- Follow-up one week after aspiration
- Adverse events
- Follow-up 2
- Follow-up 3
- Management system of participants
- Speciman management system
- Data management system
- ADR/ADE management system
- Madicine management system
- Instruments management system
- SOPs
- Research team
- Design, Methods
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nodule with high insufficient rate | high cystic nodule
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|
US assessment accords with FNA criteria recommended by C-TIRADS | Yes
/No
|
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Thyroid US indicates thyroid nodule. | Yes
|
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Age ≥ 18 years old | Yes
|
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Informed consent | Yes
|
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Patients unable to cooperate for FNA or CEUS | No
|
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Active infectious focus on cervical skin | No
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Pregnancy | No
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Severe abnormality of coagulation function | No
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Severe abnormality of heart function or lung function | No
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Refuse to CEUS | No
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Allergic to lidocaine or SonoVue | No
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Date for signing informed consent | 2023-05-16 |
|
Telephone | 13680834755 |
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Sex | Female
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Birthday | 1986-09-19 |
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Registration number | 0004327136 |
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Anteroposterior diameter | 14 mm |
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Coagulation function | Yes
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transverse diameter | 17 mm |
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Routine blood test | Yes
|
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Location of target thyroid nodule | right lobe
|
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VCs function evaluated by TLUSG | bilateral VCs moved symmetrically
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Ultrasonic diagnose | 甲状腺良性结节 |
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Rank of C-TIRADS | 3 |
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Score of C-TIRADS | 0 |
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Rank of ACR TI-RADS | 2 |
|
Score of ACR TI-RADS | 2 |
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Solid component of sheet-like strong echo (%) | - |
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Strong echo within nodule | No
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acoustic halo | No
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border | regular
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edge | clear
|
|
echo | iso-echo
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Solid component (%) | 10 |
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Upper and lower diameter | 15 mm |
- Time of aspiration
- Contrast-enhance indication (CEUS-FNA group)
- Progression of operation
- Intraoperative instant complication
|
End time | 18：01 |
|
Start time | 17：53 |
|
Date of aspiration | 2023-05-16 |
|
Injection of SonoVue during FNA | No
|
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Ratio of enhancement | 0 |
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No enhancement | Yes
|
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Dosage of SonoVue | 2 |
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Use of negative pressure | No
|
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Aspiration times | 4 |
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FNA approach | lateral approach
|
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Aspiration needle | 25G
|
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Patient compliance | good
|
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Dosage of local anaesthesics | 2.5 ml |
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other local anaesthesics | - |
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Local anesthesia | 2% lidocaine
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Machine | GE logiq E9
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Sample capacity | a little
|
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Grittiness | No
|
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Quality of nodule | Soft
|
|
Pressure | - ml |
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visible for bleeding by CDFI | |
|
location | |
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Aspiration related acute hypersensitivity reaction | No
|
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Horner syndrome | No
|
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Vagal nerve syndrome | No
|
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Voice change | No
|
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Haemorrhage | No
|
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Painful when leave interventional room | No
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Analgesic | No
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whether the voice recovers when the patient leaves | |
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VAS score | 3 |
|
methods | |
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Painful | Yes
|
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vocal cord mobility assessment by ultrasound | |
|
Allergic to contrast agent | No
|
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appearance | |
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extend of hematoma (before patient departure) | |
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visible hemorrhage by CDFI 30 minutes after FNA | |
|
methods | |
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extend of hematoma (once after FNA) |
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Whether sample capacity is enough | |
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Pathological number |
|
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Cytopathology classification | |
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Number of observable follicular epithelial cell clusters in specimen |