- Screening
- Preoperative indications
- Intraoperative indications
- Follow-up one week after aspiration
- Adverse events
- Follow-up 2
- Follow-up 3
- Management system of participants
- Speciman management system
- Data management system
- ADR/ADE management system
- Madicine management system
- Instruments management system
- SOPs
- Research team
- Design, Methods
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nodule with high insufficient rate | nodule with macrocalcification
|
|
US assessment accords with FNA criteria recommended by C-TIRADS | Yes
/No
|
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Thyroid US indicates thyroid nodule. | Yes
|
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Age ≥ 18 years old | Yes
|
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Informed consent | Yes
|
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Patients unable to cooperate for FNA or CEUS | No
|
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Active infectious focus on cervical skin | No
|
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Pregnancy | No
|
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Severe abnormality of coagulation function | No
|
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Severe abnormality of heart function or lung function | No
|
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Refuse to CEUS | No
|
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Allergic to lidocaine or SonoVue | No
|
|
Date for signing informed consent | 2023-06-25 |
|
Telephone | 18820536187 |
|
Sex | Male
|
|
Birthday | 1962-04-04 |
|
Registration number | 0001408431 |
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Anteroposterior diameter | 5 mm |
|
Coagulation function | Yes
|
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transverse diameter | 6 mm |
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Routine blood test | Yes
|
|
Location of target thyroid nodule | right lobe
|
|
VCs function evaluated by TLUSG | unassessable
|
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Ultrasonic diagnose | 甲状腺癌 |
|
Rank of C-TIRADS | 4b |
|
Score of C-TIRADS | 2 |
|
Rank of ACR TI-RADS | 5 |
|
Score of ACR TI-RADS | 9 |
|
Solid component of sheet-like strong echo (%) | 20 |
|
Strong echo within nodule | punctate
/Sheet-like
|
|
acoustic halo | No
|
|
border | angled
|
|
edge | clear
|
|
echo | hypoecho
|
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Solid component (%) | 100 |
|
Upper and lower diameter | 6 mm |
- Time of aspiration
- Contrast-enhance indication (CEUS-FNA group)
- Progression of operation
- Intraoperative instant complication
|
End time | 15：56 |
|
Start time | 15：42 |
|
Date of aspiration | 2023-06-25 |
|
Injection of SonoVue during FNA | No
|
|
Ratio of enhancement | - |
|
No enhancement | No
|
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Dosage of SonoVue | - |
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Use of negative pressure | No
|
|
Aspiration times | 4 |
|
FNA approach | lateral approach
|
|
Aspiration needle | Italy 23G
|
|
Patient compliance | good
|
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Dosage of local anaesthesics | 5 ml |
|
other local anaesthesics | - |
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Local anesthesia | 2% lidocaine
|
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Machine | GE logiq E9
|
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Sample capacity | a little
|
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Grittiness | Yes
|
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Quality of nodule | solid
|
|
Pressure | - ml |
|
vocal cord mobility assessment by ultrasound | |
|
appearance | |
|
extend of hematoma (before patient departure) | |
|
Aspiration related acute hypersensitivity reaction | No
|
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visible hemorrhage by CDFI 30 minutes after FNA | |
|
Horner syndrome | No
|
|
methods | |
|
Vagal nerve syndrome | No
|
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extend of hematoma (once after FNA) |
|
|
Voice change | No
|
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visible for bleeding by CDFI | |
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Haemorrhage | No
|
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location | |
|
Painful when leave interventional room | Yes
|
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Analgesic | No
|
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VAS score | - |
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Painful | No
|
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Allergic to contrast agent | No
|
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whether the voice recovers when the patient leaves | |
|
methods |
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Whether sample capacity is enough | |
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Pathological number |
|
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Cytopathology classification | |
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Number of observable follicular epithelial cell clusters in specimen |