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1.Screening
1.Inclusion Criteria

Whether you voluntarily participate in this study, you can complete all the follow-up contents and sign the informed consent form according to the requirements of the scheme.

yes

The subject was not treated with antiviral therapy and was evaluated by the researcher to start antiviral therapy

yes

Whether the age is above 18 (inclusive)

yes

Is it in line with the diagnostic criteria of AIDS AIDS in China (2021 edition)?

yes

2.Exclusion Criteria

Is the subject participating in other interventional clinical studies?

no

Whether the ART scheme to be launched does not belong to the two schemes included in this study?

no

2.Baseline
1.ART regimen

ART regimen

ART time

2.T lymphocyte subsets

CD4+/CD8+ratio

0.02

CD4+T cell count

12.68 cells/μL

3.Viral load

94800 copies/ml

4.Complications and treatment

Current treatment

新型隐球菌脑膜炎 肺隐球菌病 真菌败血症

Current comorbidity

Past medical history and treatment history

30余年吸烟史 约40-50支/天 20年前外伤脾破裂脾切除

5.routine blood test

WBC

5.62 ×109 /L

NEUT%

54.8 %

LY%

29.9 %

MONO%

14.4

RBC

3.07 ×10^12 /L

HGB

96 g/L

PLT

252 ×10^9 /L

Date

20240214 yyyy-mm-dd

6.Blood biochemical examination

3.6 μmol/L

7.8 μmol/L

23 U/L

Blood glucose (Glu)

6.41 mmol/L

Creatinine (Cr)

66.1 μmol/L

20 U/L

Urea nitrogen (BUN)

mmol/L

TBIL

umol/L

Chlorine (Cl)

97.7 mmol/L

Calcium (Ca)

1.84 mmol/L

Sodium (Na)

133 mmol/L

Potassium (K)

3.22 mmol/L

Albumin (Alb)

34.1 g/L

7.Urine routine

pH

WBC

/μl

ERY

/μl

GLU

mmol/L

PRO

g/L

Date

yyyy-mm-dd

8.Adverse event

Adverse event record form

3.Treatment period 12W±2W
1.

2.T lymphocyte subsets

cells/μL

3.Vital signs

Systolic pressure (SP)

mmHg

Diastolic pressure

mmHg

Temperature

degree Celsius

Position of measurement

Pulse rate

次/分

Breath frequency

次/分

Date

yyyy-mm-dd

4.Complications and treatment

5.routine blood test

WBC

×109 /L

NEUT%

%

LY%

%

MONO%

RBC

×10^12 /L

HGB

g/L

PLT

×10^9 /L

Date

yyyy-mm-dd

6.Blood biochemical examination

U/L

Blood glucose (Glu)

mmol/L

Creatinine (Cr)

μmol/L

U/L

Urea nitrogen (BUN)

mmol/L

Chlorine (Cl)

mmol/L

Calcium (Ca)

mmol/L

Sodium (Na)

mmol/L

Potassium (K)

mmol/L

Albumin (Alb)

g/L

μmol/L

μmol/L

4.Treatment period 24W±2W
1.

2.T lymphocyte subsets

cells/μL

3.Viral load

copies/ml

4.Vital signs

Systolic pressure (SP)

mmHg

Diastolic pressure

mmHg

Temperature

degree Celsius

Position of measurement

Pulse rate

次/分

Breath frequency

次/分

Date

yyyy-mm-dd

5.Complications and treatment

6.routine blood test

WBC

×109 /L

NEUT%

%

LY%

%

MONO%

RBC

×10^12 /L

HGB

g/L

PLT

×10^9 /L

Date

yyyy-mm-dd

7.Blood biochemical examination

Creatinine (Cr)

μmol/L

U/L

Urea nitrogen (BUN)

mmol/L

Chlorine (Cl)

mmol/L

Calcium (Ca)

mmol/L

Sodium (Na)

mmol/L

Potassium (K)

mmol/L

Albumin (Alb)

g/L

μmol/L

μmol/L

U/L

Blood glucose (Glu)

mmol/L

8.Urine routine

pH

WBC

/μl

ERY

/μl

GLU

mmol/L

PRO

g/L

5.Treatment period 36W±2W
1.

2.T lymphocyte subsets

cells/μL

3.Vital signs

Systolic pressure (SP)

mmHg

Diastolic pressure

mmHg

Temperature

degree Celsius

Position of measurement

Pulse rate

次/分

Breath frequency

次/分

Date

yyyy-mm-dd

4.Complications and treatment

5.routine blood test

WBC

×109 /L

NEUT%

%

LY%

%

MONO%

RBC

×10^12 /L

HGB

g/L

PLT

×10^9 /L

Date

yyyy-mm-dd

6.Blood biochemical examination

Sodium (Na)

mmol/L

Potassium (K)

mmol/L

Albumin (Alb)

g/L

μmol/L

μmol/L

U/L

Blood glucose (Glu)

mmol/L

Creatinine (Cr)

μmol/L

U/L

Urea nitrogen (BUN)

mmol/L

Chlorine (Cl)

mmol/L

Calcium (Ca)

mmol/L

6.Treatment period 48W±2W
1.

2.T lymphocyte subsets

cells/μL

3.Viral load

cells/μL

4.Vital signs

Systolic pressure (SP)

mmHg

Diastolic pressure

mmHg

Temperature

degree Celsius

Position of measurement

Pulse rate

次/分

Breath frequency

次/分

Date

yyyy-mm-dd

5.Complications and treatment

6.Routine blood test

WBC

×109 /L

NEUT%

%

LY%

%

MONO%

RBC

×10^12 /L

HGB

g/L

PLT

×10^9 /L

Date

yyyy-mm-dd

7.Blood biochemical examination

μmol/L

μmol/L

U/L

Blood glucose (Glu)

mmol/L

Creatinine (Cr)

μmol/L

U/L

Urea nitrogen (BUN)

mmol/L

Chlorine (Cl)

mmol/L

Calcium (Ca)

mmol/L

Sodium (Na)

mmol/L

Potassium (K)

mmol/L

Albumin (Alb)

g/L

8.