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1.Screening
1.1.Inclusion Criteria

age

43

1.2.Exclusion Criteria

preoperation radiotherapy

2.Baseline
2.1.Management of the progress
2.2.General information
2.3.Physical examination
3.Perioperative data
4.Follow-up data
4.1.One month after surgery

Constant score

4.2.Three month after surgery

constant

4.3.Six month after surgery

constant

4.4.Nine month after surgery

constant

4.5.Twelve month after surgery

constant

15.Research team
15.1.Institutions
15.2.Researchers
16.Design, Methods
16.1.Calculation of sample size
17.Follow-up
17.1.Management for Progress