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1.Screening
1.1.Inclusion Criteria

Age ≥ 65 years

ASA Classification II-III

3D-CAM method to determine the absence of pre-existing delirium before surgery

Score ≥15 on the Brief Mental State Examination scale

1.2.Exclusion Criteria

Previous history of neurological or psychiatric disorders

Long-term use of sedative-hypnotic, antipsychotic drugs

Severe visual and hearing impairment

Combined heart, lung, liver, kidney and other vital organ dysfunction

2.Baseline
2.1.General information

Type of surgery

genders

age

Length of education

BMI

ASA classification

MMSE scores

smoking history

drinking history

Number of preoperative chemotherapy treatments

high blood pressure

diabetes

coronary heart disease

Preoperative hemoglobin

g/L

Preoperative albumin

g/L

Preoperative SII

3.In the process of the treatment
3.1.Intraoperative information

Surgical time

min

propofol

mg

cis-Atracurium

mg

sufentanil

ug

remifentanil

mg

Ephedrine

mg

Atropine

mg

Urapidil

mg

red blood cell suspension

U

Plasma transfusion

ml

fluid infusion

ml

hemorrhage

ml

urine output

ml

Average CSI value

Duration of EEG burst suppression

s

Preoperative MAP T0

mmHg

Preoperative heart rate T0

次/分

Pre-induction MAP T1

mmHg

Pre-induction heart rate T1

次/分

Post-induction MAP T2

mmHg

Post-induction heart rate T2

次/分

Average MAP T3

mmHg

Average heart rate T3

次/分

Out of the operating room MAP T4

mmHg

Heart rate out of the operating room T4

次/分

4.At the end of the treatment
4.1.Post-operative information

Extraction time

min

PACU dwell time

min

Days of hospitalization

Arrhythmia/Heart Failure/Heart Attack

cutaneous infection

lung infection

nausea and vomiting

DVT/PTE

Postoperative day one SII

Postoperative day three SII

Postoperative day five SII

5.Follow-up 1
5.1.5-day post-treatment visit

POD on the first postoperative day

POD on the second day postoperatively

POD on the third postoperative day

POD on the fourth postoperative day

POD on the fifth postoperative day

VAS score on the first day postoperatively

VAS score on the second day after surgery

VAS score on the third postoperative day

VAS score on the fourth postoperative day

VAS score on the fifth postoperative day