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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

70

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

29

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

178.5 mmHg

Heart Rate

70 t/s

Diastolic Blood Pressure

73.5 mmHg

Body Weight

61.7 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

11

2.2.2.2.2.2、Part II

Total Score

25

2.2.2.2.2.3、Part III

Total Score

59

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

9

2.3.NMSS

Total Score

158

2.4.PDQ-39

Total Score

103

2.5.SF-36

Part 1 Score

5

Part 2 Score

5

Part 3 Score

21

Part 4 Score

8

Part 5 Score

12

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

29

Part 10 Score

3

Part 11 Score

13

2.6.DSQ

Total Score

13

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

148.5 mmHg

Diastolic Blood Pressure

73.5 mmHg

Heart Rate

63.5 t/s

Body Weight

59.6 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

17

3.3.2.3.2.2、Part II

Total Score

28

3.3.2.3.2.3、Part III

Total Score

56

Dyskinesias

Interfere with ratings

H&Y Stage

3

3.3.2.3.2.4、Part IV

Total Score

10

3.3.NMSS

Total Score

173

3.4.PDQ-39

Total Score

110

3.5.SF-36

Part 1 Score

5

Part 2 Score

4

Part 3 Score

20

Part 4 Score

10

Part 5 Score

15

Part 6 Score

5

Part 7 Score

3

Part 8 Score

2

Part 9 Score

25

Part 10 Score

2

Part 11 Score

12

3.6.DSQ

Total Score

13

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

147 mmHg

Heart Rate

63.5 t/s

Diastolic Blood Pressure

66.5 mmHg

Body Weight

58.4 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

24

4.4.2.4.2.2、Part II

Total Score

28

4.4.2.4.2.3、Part III

Total Score

61

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

10

4.3.NMSS

Total Score

176

4.4.PDQ-39

Total Score

99

4.5.SF-36

Part 1 Score

5

Part 2 Score

4

Part 3 Score

15

Part 4 Score

14

Part 5 Score

11

Part 6 Score

4

Part 7 Score

6

Part 8 Score

5

Part 9 Score

27

Part 10 Score

2

Part 11 Score

13

4.6.DSQ

Total Score

14

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

157.5 mmHg

Diastolic Blood Pressure

65.5 mmHg

Heart Rate

62.5 t/s

Body Weight

59.3 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

31

5.5.2.5.2.2、Part II

Total Score

30

5.5.2.5.2.3、Part III

Total Score

63

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

9

5.3.NMSS

Total Score

155

5.4.PDQ-39

Total Score

99

5.5.SF-36

Part 1 Score

5

Part 2 Score

4

Part 3 Score

13

Part 4 Score

6

Part 5 Score

14

Part 6 Score

4

Part 7 Score

2

Part 8 Score

2

Part 9 Score

28

Part 10 Score

2

Part 11 Score

12

5.6.DSQ

Total Score

15

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