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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

61

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

29

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

115 mmHg

Heart Rate

59 t/s

Diastolic Blood Pressure

80.5 mmHg

Body Weight

86.3 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

3

2.2.2.2.2.2、Part II

Total Score

3

2.2.2.2.2.3、Part III

Total Score

10

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

37

2.4.PDQ-39

Total Score

7

2.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

28

Part 4 Score

13

Part 5 Score

9

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

27

Part 10 Score

3

Part 11 Score

11

2.6.DSQ

Total Score

3

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

147.5 mmHg

Diastolic Blood Pressure

100 mmHg

Heart Rate

64 t/s

Body Weight

85.9 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

2

3.3.2.3.2.2、Part II

Total Score

1

3.3.2.3.2.3、Part III

Total Score

6

Dyskinesias

Interfere with ratings

H&Y Stage

1

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

14

3.4.PDQ-39

Total Score

3

3.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

29

Part 4 Score

20

Part 5 Score

15

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

32

Part 10 Score

5

Part 11 Score

12

3.6.DSQ

Total Score

0

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

125 mmHg

Heart Rate

50.5 t/s

Diastolic Blood Pressure

84 mmHg

Body Weight

85.1 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

3

4.4.2.4.2.2、Part II

Total Score

2

4.4.2.4.2.3、Part III

Total Score

12

Dyskinesias

Interfere with ratings

H&Y Stage

1

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

21

4.4.PDQ-39

Total Score

11

4.5.SF-36

Part 1 Score

2

Part 2 Score

3

Part 3 Score

29

Part 4 Score

16

Part 5 Score

13

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

35

Part 10 Score

5

Part 11 Score

15

4.6.DSQ

Total Score

4

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

131 mmHg

Diastolic Blood Pressure

58 mmHg

Heart Rate

87 t/s

Body Weight

86.1 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

5

5.5.2.5.2.2、Part II

Total Score

4

5.5.2.5.2.3、Part III

Total Score

11

Dyskinesias

Interfere with ratings

H&Y Stage

1

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

30

5.4.PDQ-39

Total Score

7

5.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

30

Part 4 Score

19

Part 5 Score

14

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

31

Part 10 Score

5

Part 11 Score

16

5.6.DSQ

Total Score

4

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