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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

64

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

3

Mini-Mental State Examination

24

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

108.5 mmHg

Heart Rate

76 t/s

Diastolic Blood Pressure

71 mmHg

Body Weight

54.7 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

24

2.2.2.2.2.2、Part II

Total Score

22

2.2.2.2.2.3、Part III

Total Score

53

Dyskinesias

Interfere with ratings

H&Y Stage

3

2.2.2.2.2.4、Part IV

Total Score

7

2.3.NMSS

Total Score

155

2.4.PDQ-39

Total Score

99

2.5.SF-36

Part 1 Score

4

Part 2 Score

2

Part 3 Score

23

Part 4 Score

10

Part 5 Score

8

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

24

Part 10 Score

1

Part 11 Score

13

2.6.DSQ

Total Score

13

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

131 mmHg

Diastolic Blood Pressure

82 mmHg

Heart Rate

77.5 t/s

Body Weight

53.4 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

23

3.3.2.3.2.2、Part II

Total Score

24

3.3.2.3.2.3、Part III

Total Score

51

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

158

3.4.PDQ-39

Total Score

75

3.5.SF-36

Part 1 Score

5

Part 2 Score

3

Part 3 Score

21

Part 4 Score

13

Part 5 Score

8

Part 6 Score

4

Part 7 Score

3

Part 8 Score

3

Part 9 Score

24

Part 10 Score

3

Part 11 Score

12

3.6.DSQ

Total Score

7

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

110.5 mmHg

Heart Rate

78 t/s

Diastolic Blood Pressure

67.5 mmHg

Body Weight

52.7 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

18

4.4.2.4.2.2、Part II

Total Score

18

4.4.2.4.2.3、Part III

Total Score

58

Dyskinesias

Interfere with ratings

H&Y Stage

3

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

110

4.4.PDQ-39

Total Score

71

4.5.SF-36

Part 1 Score

4

Part 2 Score

4

Part 3 Score

24

Part 4 Score

9

Part 5 Score

8

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

32

Part 10 Score

2

Part 11 Score

12

4.6.DSQ

Total Score

7

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

114 mmHg

Diastolic Blood Pressure

64 mmHg

Heart Rate

71.5 t/s

Body Weight

53.7 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

22

5.5.2.5.2.2、Part II

Total Score

28

5.5.2.5.2.3、Part III

Total Score

59

Dyskinesias

Interfere with ratings

H&Y Stage

3

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

148

5.4.PDQ-39

Total Score

87

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

10

Part 5 Score

7

Part 6 Score

3

Part 7 Score

4

Part 8 Score

4

Part 9 Score

27

Part 10 Score

2

Part 11 Score

15

5.6.DSQ

Total Score

9

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