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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Age

DSQ

Stable treatment history for at least 4 weeks

Modified Hoehn and Yahr scale

Mini-Mental State Examination
1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

120 mmHg

Heart Rate

60 t/s

Diastolic Blood Pressure

66 mmHg

Body Weight

65.5 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

6

2.2.2.2.2.2、Part II

Total Score

13

2.2.2.2.2.3、Part III

Total Score

43

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

41

2.4.PDQ-39

Total Score

15

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

16

Part 5 Score

13

Part 6 Score

2

Part 7 Score

3

Part 8 Score

3

Part 9 Score

33

Part 10 Score

4

Part 11 Score

14

2.6.DSQ

Total Score

7

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

104 mmHg

Diastolic Blood Pressure

63.5 mmHg

Heart Rate

81 t/s

Body Weight

65.6 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

16

3.3.2.3.2.2、Part II

Total Score

15

3.3.2.3.2.3、Part III

Total Score

43

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

63

3.4.PDQ-39

Total Score

34

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

26

Part 4 Score

17

Part 5 Score

12

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

27

Part 10 Score

3

Part 11 Score

10

3.6.DSQ

Total Score

8

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

112 mmHg

Heart Rate

85 t/s

Diastolic Blood Pressure

67.5 mmHg

Body Weight

66 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

11

4.4.2.4.2.2、Part II

Total Score

11

4.4.2.4.2.3、Part III

Total Score

45

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

7

4.3.NMSS

Total Score

59

4.4.PDQ-39

Total Score

25

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

26

Part 4 Score

15

Part 5 Score

12

Part 6 Score

1

Part 7 Score

4

Part 8 Score

3

Part 9 Score

34

Part 10 Score

4

Part 11 Score

14

4.6.DSQ

Total Score

6

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

111.5 mmHg

Diastolic Blood Pressure

67 mmHg

Heart Rate

84 t/s

Body Weight

64.6 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

18

5.5.2.5.2.2、Part II

Total Score

13

5.5.2.5.2.3、Part III

Total Score

47

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

5

5.3.NMSS

Total Score

72

5.4.PDQ-39

Total Score

25

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

25

Part 4 Score

15

Part 5 Score

12

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

33

Part 10 Score

4

Part 11 Score

15

5.6.DSQ

Total Score

7

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