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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

69

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

30

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding

2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

127 mmHg

Heart Rate

73.5 t/s

Diastolic Blood Pressure

77 mmHg

Body Weight

63.6 kg

General Consultation

2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

7

2.2.2.2.2.2、Part II

Total Score

13

2.2.2.2.2.3、Part III

Total Score

47

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

7

2.3.NMSS

Total Score

28

2.4.PDQ-39

Total Score

10

2.5.SF-36

Part 1 Score

2

Part 2 Score

3

Part 3 Score

27

Part 4 Score

10

Part 5 Score

12

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

30

Part 10 Score

5

Part 11 Score

11

2.6.DSQ

Total Score

5

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

114 mmHg

Diastolic Blood Pressure

64.5 mmHg

Heart Rate

83 t/s

Body Weight

65.7 kg

General Consultation

3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

4

3.3.2.3.2.2、Part II

Total Score

14

3.3.2.3.2.3、Part III

Total Score

35

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

10

3.3.NMSS

Total Score

22

3.4.PDQ-39

Total Score

5

3.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

28

Part 4 Score

20

Part 5 Score

15

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

33

Part 10 Score

5

Part 11 Score

15

3.6.DSQ

Total Score

6

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

107.5 mmHg

Heart Rate

68.5 t/s

Diastolic Blood Pressure

61 mmHg

Body Weight

65 kg

General Consultation

4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

4

4.4.2.4.2.2、Part II

Total Score

10

4.4.2.4.2.3、Part III

Total Score

36

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

7

4.3.NMSS

Total Score

25

4.4.PDQ-39

Total Score

11

4.5.SF-36

Part 1 Score

2

Part 2 Score

3

Part 3 Score

29

Part 4 Score

17

Part 5 Score

15

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

33

Part 10 Score

5

Part 11 Score

13

4.6.DSQ

Total Score

8

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

111.5 mmHg

Diastolic Blood Pressure

63 mmHg

Heart Rate

70 t/s

Body Weight

65.8 kg

General Consultation

5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

7

5.5.2.5.2.2、Part II

Total Score

12

5.5.2.5.2.3、Part III

Total Score

26

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

6

5.3.NMSS

Total Score

21

5.4.PDQ-39

Total Score

9

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

29

Part 4 Score

17

Part 5 Score

14

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

33

Part 10 Score

5

Part 11 Score

13

5.6.DSQ

Total Score

4