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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

70

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

30

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

96.5 mmHg

Heart Rate

71.5 t/s

Diastolic Blood Pressure

57 mmHg

Body Weight

65.2 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

6

2.2.2.2.2.2、Part II

Total Score

9

2.2.2.2.2.3、Part III

Total Score

21

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

65

2.4.PDQ-39

Total Score

20

2.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

29

Part 4 Score

18

Part 5 Score

14

Part 6 Score

1

Part 7 Score

4

Part 8 Score

3

Part 9 Score

28

Part 10 Score

5

Part 11 Score

15

2.6.DSQ

Total Score

10

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

97.5 mmHg

Diastolic Blood Pressure

51 mmHg

Heart Rate

71.5 t/s

Body Weight

65.6 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

10

3.3.2.3.2.2、Part II

Total Score

7

3.3.2.3.2.3、Part III

Total Score

27

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

42

3.4.PDQ-39

Total Score

14

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

18

Part 5 Score

15

Part 6 Score

1

Part 7 Score

4

Part 8 Score

3

Part 9 Score

34

Part 10 Score

5

Part 11 Score

15

3.6.DSQ

Total Score

8

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

110 mmHg

Heart Rate

64 t/s

Diastolic Blood Pressure

71 mmHg

Body Weight

64.9 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

9

4.4.2.4.2.2、Part II

Total Score

8

4.4.2.4.2.3、Part III

Total Score

27

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

36

4.4.PDQ-39

Total Score

18

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

18

Part 5 Score

15

Part 6 Score

1

Part 7 Score

4

Part 8 Score

3

Part 9 Score

29

Part 10 Score

5

Part 11 Score

17

4.6.DSQ

Total Score

6

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

101.5 mmHg

Diastolic Blood Pressure

57 mmHg

Heart Rate

77 t/s

Body Weight

64.6 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

7

5.5.2.5.2.2、Part II

Total Score

9

5.5.2.5.2.3、Part III

Total Score

32

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

33

5.4.PDQ-39

Total Score

15

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

16

Part 5 Score

15

Part 6 Score

1

Part 7 Score

5

Part 8 Score

3

Part 9 Score

35

Part 10 Score

5

Part 11 Score

12

5.6.DSQ

Total Score

7

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