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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

63

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

28

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

143.5 mmHg

Heart Rate

61 t/s

Diastolic Blood Pressure

75 mmHg

Body Weight

50.2 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

2

2.2.2.2.2.2、Part II

Total Score

8

2.2.2.2.2.3、Part III

Total Score

22

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

14

2.4.PDQ-39

Total Score

28

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

26

Part 4 Score

19

Part 5 Score

14

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

33

Part 10 Score

5

Part 11 Score

13

2.6.DSQ

Total Score

6

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

128.5 mmHg

Diastolic Blood Pressure

72.5 mmHg

Heart Rate

58 t/s

Body Weight

49.6 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

5

3.3.2.3.2.2、Part II

Total Score

13

3.3.2.3.2.3、Part III

Total Score

19

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

25

3.4.PDQ-39

Total Score

24

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

19

Part 5 Score

14

Part 6 Score

1

Part 7 Score

3

Part 8 Score

3

Part 9 Score

29

Part 10 Score

5

Part 11 Score

14

3.6.DSQ

Total Score

7

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

125 mmHg

Heart Rate

69 t/s

Diastolic Blood Pressure

57.5 mmHg

Body Weight

50.3 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

4

4.4.2.4.2.2、Part II

Total Score

11

4.4.2.4.2.3、Part III

Total Score

13

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

33

4.4.PDQ-39

Total Score

23

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

25

Part 4 Score

19

Part 5 Score

14

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

34

Part 10 Score

5

Part 11 Score

14

4.6.DSQ

Total Score

6

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

134 mmHg

Diastolic Blood Pressure

71.5 mmHg

Heart Rate

59 t/s

Body Weight

51 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

6

5.5.2.5.2.2、Part II

Total Score

12

5.5.2.5.2.3、Part III

Total Score

18

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

28

5.4.PDQ-39

Total Score

18

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

18

Part 5 Score

14

Part 6 Score

1

Part 7 Score

4

Part 8 Score

3

Part 9 Score

29

Part 10 Score

4

Part 11 Score

14

5.6.DSQ

Total Score

6

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