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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

74

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

26

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

144 mmHg

Heart Rate

73.5 t/s

Diastolic Blood Pressure

84.5 mmHg

Body Weight

63.6 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

11

2.2.2.2.2.2、Part II

Total Score

13

2.2.2.2.2.3、Part III

Total Score

26

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

6

2.3.NMSS

Total Score

44

2.4.PDQ-39

Total Score

33

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

23

Part 4 Score

11

Part 5 Score

13

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

31

Part 10 Score

3

Part 11 Score

10

2.6.DSQ

Total Score

11

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

104 mmHg

Diastolic Blood Pressure

64 mmHg

Heart Rate

78.5 t/s

Body Weight

62.8 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

11

3.3.2.3.2.2、Part II

Total Score

13

3.3.2.3.2.3、Part III

Total Score

19

Dyskinesias

Interfere with ratings

H&Y Stage

1

3.3.2.3.2.4、Part IV

Total Score

8

3.3.NMSS

Total Score

87

3.4.PDQ-39

Total Score

27

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

25

Part 4 Score

12

Part 5 Score

9

Part 6 Score

3

Part 7 Score

3

Part 8 Score

3

Part 9 Score

31

Part 10 Score

3

Part 11 Score

15

3.6.DSQ

Total Score

8

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

115.5 mmHg

Heart Rate

80 t/s

Diastolic Blood Pressure

67.5 mmHg

Body Weight

64.2 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

17

4.4.2.4.2.2、Part II

Total Score

7

4.4.2.4.2.3、Part III

Total Score

25

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

5

4.3.NMSS

Total Score

94

4.4.PDQ-39

Total Score

24

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

25

Part 4 Score

16

Part 5 Score

12

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

32

Part 10 Score

4

Part 11 Score

13

4.6.DSQ

Total Score

10

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

98 mmHg

Diastolic Blood Pressure

56.5 mmHg

Heart Rate

89 t/s

Body Weight

64.1 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

15

5.5.2.5.2.2、Part II

Total Score

8

5.5.2.5.2.3、Part III

Total Score

24

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

6

5.3.NMSS

Total Score

66

5.4.PDQ-39

Total Score

26

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

27

Part 4 Score

15

Part 5 Score

9

Part 6 Score

3

Part 7 Score

3

Part 8 Score

3

Part 9 Score

30

Part 10 Score

3

Part 11 Score

15

5.6.DSQ

Total Score

15

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