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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

61

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

27

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

118.5 mmHg

Heart Rate

57.5 t/s

Diastolic Blood Pressure

68.5 mmHg

Body Weight

56.7 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

15

2.2.2.2.2.2、Part II

Total Score

12

2.2.2.2.2.3、Part III

Total Score

18

Dyskinesias

Interfere with ratings

H&Y Stage

3

2.2.2.2.2.4、Part IV

Total Score

2

2.3.NMSS

Total Score

80

2.4.PDQ-39

Total Score

67

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

22

Part 4 Score

13

Part 5 Score

11

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

26

Part 10 Score

2

Part 11 Score

12

2.6.DSQ

Total Score

5

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

125 mmHg

Diastolic Blood Pressure

66.5 mmHg

Heart Rate

69.5 t/s

Body Weight

56.8 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

11

3.3.2.3.2.2、Part II

Total Score

11

3.3.2.3.2.3、Part III

Total Score

27

Dyskinesias

Interfere with ratings

H&Y Stage

3

3.3.2.3.2.4、Part IV

Total Score

1

3.3.NMSS

Total Score

53

3.4.PDQ-39

Total Score

34

3.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

26

Part 4 Score

16

Part 5 Score

13

Part 6 Score

1

Part 7 Score

5

Part 8 Score

4

Part 9 Score

34

Part 10 Score

5

Part 11 Score

11

3.6.DSQ

Total Score

3

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

143 mmHg

Heart Rate

63 t/s

Diastolic Blood Pressure

92 mmHg

Body Weight

56.9 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

9

4.4.2.4.2.2、Part II

Total Score

15

4.4.2.4.2.3、Part III

Total Score

23

Dyskinesias

Yes

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

11

4.3.NMSS

Total Score

48

4.4.PDQ-39

Total Score

46

4.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

22

Part 4 Score

14

Part 5 Score

14

Part 6 Score

1

Part 7 Score

4

Part 8 Score

3

Part 9 Score

32

Part 10 Score

2

Part 11 Score

14

4.6.DSQ

Total Score

4

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

116.5 mmHg

Diastolic Blood Pressure

66 mmHg

Heart Rate

67.5 t/s

Body Weight

55.9 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

14

5.5.2.5.2.2、Part II

Total Score

16

5.5.2.5.2.3、Part III

Total Score

30

Dyskinesias

Yes

Interfere with ratings

Yes

H&Y Stage

3

5.5.2.5.2.4、Part IV

Total Score

11

5.3.NMSS

Total Score

86

5.4.PDQ-39

Total Score

49

5.5.SF-36

Part 1 Score

5

Part 2 Score

3

Part 3 Score

25

Part 4 Score

16

Part 5 Score

11

Part 6 Score

4

Part 7 Score

5

Part 8 Score

4

Part 9 Score

36

Part 10 Score

3

Part 11 Score

9

5.6.DSQ

Total Score

5

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