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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

72

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

25

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

139.5 mmHg

Heart Rate

71.5 t/s

Diastolic Blood Pressure

75 mmHg

Body Weight

61 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

15

2.2.2.2.2.2、Part II

Total Score

22

2.2.2.2.2.3、Part III

Total Score

27

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

78

2.4.PDQ-39

Total Score

58

2.5.SF-36

Part 1 Score

3

Part 2 Score

3

Part 3 Score

21

Part 4 Score

13

Part 5 Score

9

Part 6 Score

3

Part 7 Score

4

Part 8 Score

3

Part 9 Score

34

Part 10 Score

3

Part 11 Score

14

2.6.DSQ

Total Score

7

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

140 mmHg

Diastolic Blood Pressure

74.5 mmHg

Heart Rate

66 t/s

Body Weight

60.9 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

15

3.3.2.3.2.2、Part II

Total Score

26

3.3.2.3.2.3、Part III

Total Score

40

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

2

3.3.NMSS

Total Score

73

3.4.PDQ-39

Total Score

72

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

16

Part 5 Score

12

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

33

Part 10 Score

3

Part 11 Score

12

3.6.DSQ

Total Score

5

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

152 mmHg

Heart Rate

76 t/s

Diastolic Blood Pressure

83.5 mmHg

Body Weight

60.1 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

14

4.4.2.4.2.2、Part II

Total Score

23

4.4.2.4.2.3、Part III

Total Score

31

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

100

4.4.PDQ-39

Total Score

63

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

19

Part 4 Score

16

Part 5 Score

12

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

38

Part 10 Score

2

Part 11 Score

14

4.6.DSQ

Total Score

5

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

126 mmHg

Diastolic Blood Pressure

72 mmHg

Heart Rate

74.5 t/s

Body Weight

61.3 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

17

5.5.2.5.2.2、Part II

Total Score

22

5.5.2.5.2.3、Part III

Total Score

30

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

138

5.4.PDQ-39

Total Score

71

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

25

Part 4 Score

16

Part 5 Score

12

Part 6 Score

2

Part 7 Score

2

Part 8 Score

3

Part 9 Score

35

Part 10 Score

2

Part 11 Score

13

5.6.DSQ

Total Score

7

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