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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

71

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

29

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

116.5 mmHg

Heart Rate

61.5 t/s

Diastolic Blood Pressure

68 mmHg

Body Weight

56 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

9

2.2.2.2.2.2、Part II

Total Score

6

2.2.2.2.2.3、Part III

Total Score

30

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

4

2.3.NMSS

Total Score

31

2.4.PDQ-39

Total Score

31

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

11

Part 5 Score

11

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

39

Part 10 Score

3

Part 11 Score

15

2.6.DSQ

Total Score

6

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

113.5 mmHg

Diastolic Blood Pressure

62 mmHg

Heart Rate

61.5 t/s

Body Weight

55.3 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

7

3.3.2.3.2.2、Part II

Total Score

14

3.3.2.3.2.3、Part III

Total Score

45

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

5

3.3.NMSS

Total Score

42

3.4.PDQ-39

Total Score

26

3.5.SF-36

Part 1 Score

3

Part 2 Score

2

Part 3 Score

30

Part 4 Score

17

Part 5 Score

12

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

37

Part 10 Score

3

Part 11 Score

16

3.6.DSQ

Total Score

8

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

119 mmHg

Heart Rate

71.5 t/s

Diastolic Blood Pressure

75 mmHg

Body Weight

55.4 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

6

4.4.2.4.2.2、Part II

Total Score

10

4.4.2.4.2.3、Part III

Total Score

33

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

3

4.3.NMSS

Total Score

31

4.4.PDQ-39

Total Score

21

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

28

Part 4 Score

15

Part 5 Score

15

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

40

Part 10 Score

3

Part 11 Score

13

4.6.DSQ

Total Score

7

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

135.5 mmHg

Diastolic Blood Pressure

66 mmHg

Heart Rate

77.5 t/s

Body Weight

56.6 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

3

5.5.2.5.2.2、Part II

Total Score

13

5.5.2.5.2.3、Part III

Total Score

33

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

3

5.3.NMSS

Total Score

20

5.4.PDQ-39

Total Score

13

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

29

Part 4 Score

18

Part 5 Score

15

Part 6 Score

1

Part 7 Score

1

Part 8 Score

1

Part 9 Score

40

Part 10 Score

5

Part 11 Score

15

5.6.DSQ

Total Score

6

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