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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

74

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

2

Mini-Mental State Examination

25

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

139 mmHg

Heart Rate

72 t/s

Diastolic Blood Pressure

78.5 mmHg

Body Weight

69.1 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

20

2.2.2.2.2.2、Part II

Total Score

29

2.2.2.2.2.3、Part III

Total Score

53

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

150

2.4.PDQ-39

Total Score

72

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

16

Part 4 Score

5

Part 5 Score

8

Part 6 Score

4

Part 7 Score

4

Part 8 Score

3

Part 9 Score

22

Part 10 Score

2

Part 11 Score

13

2.6.DSQ

Total Score

15

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

114.5 mmHg

Diastolic Blood Pressure

70.5 mmHg

Heart Rate

81.5 t/s

Body Weight

66.4 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

11

3.3.2.3.2.2、Part II

Total Score

25

3.3.2.3.2.3、Part III

Total Score

59

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

83

3.4.PDQ-39

Total Score

61

3.5.SF-36

Part 1 Score

4

Part 2 Score

4

Part 3 Score

18

Part 4 Score

12

Part 5 Score

9

Part 6 Score

1

Part 7 Score

3

Part 8 Score

3

Part 9 Score

27

Part 10 Score

3

Part 11 Score

14

3.6.DSQ

Total Score

11

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

116 mmHg

Heart Rate

81.5 t/s

Diastolic Blood Pressure

70.5 mmHg

Body Weight

65.6 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

19

4.4.2.4.2.2、Part II

Total Score

24

4.4.2.4.2.3、Part III

Total Score

66

Dyskinesias

Interfere with ratings

H&Y Stage

3

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

170

4.4.PDQ-39

Total Score

74

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

16

Part 4 Score

10

Part 5 Score

7

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

30

Part 10 Score

1

Part 11 Score

14

4.6.DSQ

Total Score

13

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

143 mmHg

Diastolic Blood Pressure

80 mmHg

Heart Rate

79.5 t/s

Body Weight

66.4 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

20

5.5.2.5.2.2、Part II

Total Score

27

5.5.2.5.2.3、Part III

Total Score

72

Dyskinesias

Interfere with ratings

H&Y Stage

2

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

113

5.4.PDQ-39

Total Score

67

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

14

Part 4 Score

6

Part 5 Score

3

Part 6 Score

4

Part 7 Score

5

Part 8 Score

4

Part 9 Score

31

Part 10 Score

1

Part 11 Score

12

5.6.DSQ

Total Score

11

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