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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

71

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

3

Mini-Mental State Examination

28

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

142 mmHg

Heart Rate

62 t/s

Diastolic Blood Pressure

70.5 mmHg

Body Weight

51.7 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

2

2.2.2.2.2.2、Part II

Total Score

10

2.2.2.2.2.3、Part III

Total Score

26

Dyskinesias

Interfere with ratings

H&Y Stage

3

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

54

2.4.PDQ-39

Total Score

12

2.5.SF-36

Part 1 Score

4

Part 2 Score

2

Part 3 Score

24

Part 4 Score

11

Part 5 Score

15

Part 6 Score

3

Part 7 Score

3

Part 8 Score

2

Part 9 Score

31

Part 10 Score

3

Part 11 Score

12

2.6.DSQ

Total Score

5

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

119 mmHg

Diastolic Blood Pressure

64.5 mmHg

Heart Rate

65.5 t/s

Body Weight

50.9 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

5

3.3.2.3.2.2、Part II

Total Score

8

3.3.2.3.2.3、Part III

Total Score

27

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

44

3.4.PDQ-39

Total Score

13

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

14

Part 5 Score

15

Part 6 Score

3

Part 7 Score

4

Part 8 Score

2

Part 9 Score

30

Part 10 Score

5

Part 11 Score

14

3.6.DSQ

Total Score

7

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

121.5 mmHg

Heart Rate

65.5 t/s

Diastolic Blood Pressure

66 mmHg

Body Weight

53 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

6

4.4.2.4.2.2、Part II

Total Score

10

4.4.2.4.2.3、Part III

Total Score

29

Dyskinesias

Interfere with ratings

H&Y Stage

2

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

29

4.4.PDQ-39

Total Score

13

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

12

Part 5 Score

15

Part 6 Score

3

Part 7 Score

3

Part 8 Score

2

Part 9 Score

30

Part 10 Score

3

Part 11 Score

16

4.6.DSQ

Total Score

8

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

108.5 mmHg

Diastolic Blood Pressure

58.5 mmHg

Heart Rate

68.5 t/s

Body Weight

53 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

8

5.5.2.5.2.2、Part II

Total Score

12

5.5.2.5.2.3、Part III

Total Score

39

Dyskinesias

Interfere with ratings

H&Y Stage

3

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

43

5.4.PDQ-39

Total Score

37

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

26

Part 4 Score

16

Part 5 Score

15

Part 6 Score

3

Part 7 Score

3

Part 8 Score

3

Part 9 Score

34

Part 10 Score

5

Part 11 Score

15

5.6.DSQ

Total Score

8

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