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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

52

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

1

Mini-Mental State Examination

25

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

143.5 mmHg

Heart Rate

91 t/s

Diastolic Blood Pressure

78.5 mmHg

Body Weight

58.6 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

10

2.2.2.2.2.2、Part II

Total Score

15

2.2.2.2.2.3、Part III

Total Score

30

Dyskinesias

Interfere with ratings

H&Y Stage

2

2.2.2.2.2.4、Part IV

Total Score

0

2.3.NMSS

Total Score

44

2.4.PDQ-39

Total Score

47

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

13

Part 5 Score

14

Part 6 Score

2

Part 7 Score

3

Part 8 Score

2

Part 9 Score

35

Part 10 Score

4

Part 11 Score

17

2.6.DSQ

Total Score

6

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

159 mmHg

Diastolic Blood Pressure

87 mmHg

Heart Rate

88.5 t/s

Body Weight

56.5 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

11

3.3.2.3.2.2、Part II

Total Score

13

3.3.2.3.2.3、Part III

Total Score

32

Dyskinesias

Interfere with ratings

H&Y Stage

2

3.3.2.3.2.4、Part IV

Total Score

0

3.3.NMSS

Total Score

49

3.4.PDQ-39

Total Score

52

3.5.SF-36

Part 1 Score

4

Part 2 Score

4

Part 3 Score

25

Part 4 Score

12

Part 5 Score

10

Part 6 Score

3

Part 7 Score

3

Part 8 Score

2

Part 9 Score

24

Part 10 Score

5

Part 11 Score

13

3.6.DSQ

Total Score

12

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

134 mmHg

Heart Rate

97 t/s

Diastolic Blood Pressure

77.5 mmHg

Body Weight

55.2 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

9

4.4.2.4.2.2、Part II

Total Score

17

4.4.2.4.2.3、Part III

Total Score

42

Dyskinesias

Interfere with ratings

H&Y Stage

3

4.4.2.4.2.4、Part IV

Total Score

0

4.3.NMSS

Total Score

51

4.4.PDQ-39

Total Score

33

4.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

25

Part 4 Score

16

Part 5 Score

9

Part 6 Score

3

Part 7 Score

1

Part 8 Score

1

Part 9 Score

31

Part 10 Score

4

Part 11 Score

16

4.6.DSQ

Total Score

10

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

141 mmHg

Diastolic Blood Pressure

82 mmHg

Heart Rate

91.5 t/s

Body Weight

53.7 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

23

5.5.2.5.2.2、Part II

Total Score

19

5.5.2.5.2.3、Part III

Total Score

51

Dyskinesias

Interfere with ratings

H&Y Stage

3

5.5.2.5.2.4、Part IV

Total Score

0

5.3.NMSS

Total Score

70

5.4.PDQ-39

Total Score

56

5.5.SF-36

Part 1 Score

5

Part 2 Score

4

Part 3 Score

18

Part 4 Score

8

Part 5 Score

7

Part 6 Score

4

Part 7 Score

4

Part 8 Score

4

Part 9 Score

27

Part 10 Score

2

Part 11 Score

16

5.6.DSQ

Total Score

14

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