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1.Screening
1.1.Inclusion criteria

Diagnosed by Western Medicine

Yes

Age

75

DSQ

Yes

Stable treatment history for at least 4 weeks

Yes

Modified Hoehn and Yahr scale

3

Mini-Mental State Examination

24

1.2.Exclusion criteria

With at least one disease as listed following:

Allergy to Chinese herbal medicine

Pregnancy or are breast feeding
2.Baseline
2.1.Physical Examination

Systolic Blood Pressure

127.5 mmHg

Heart Rate

60.5 t/s

Diastolic Blood Pressure

71 mmHg

Body Weight

61.6 kg

General Consultation
2.2.MDS-UPDRS
2.2.2.2.2.1、Part I

Total Score

14

2.2.2.2.2.2、Part II

Total Score

20

2.2.2.2.2.3、Part III

Total Score

39

Dyskinesias

Interfere with ratings

H&Y Stage

3

2.2.2.2.2.4、Part IV

Total Score

9

2.3.NMSS

Total Score

64

2.4.PDQ-39

Total Score

62

2.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

27

Part 4 Score

9

Part 5 Score

8

Part 6 Score

4

Part 7 Score

2

Part 8 Score

3

Part 9 Score

25

Part 10 Score

3

Part 11 Score

11

2.6.DSQ

Total Score

10

3.Half of Treatment(16 week)
3.1.Physical Examination

Systolic Blood Pressure

131.5 mmHg

Diastolic Blood Pressure

72 mmHg

Heart Rate

61 t/s

Body Weight

63.1 kg

General Consultation
3.2.MDS-UPDRS
3.3.2.3.2.1、Part I

Total Score

15

3.3.2.3.2.2、Part II

Total Score

25

3.3.2.3.2.3、Part III

Total Score

53

Dyskinesias

Interfere with ratings

H&Y Stage

4

3.3.2.3.2.4、Part IV

Total Score

6

3.3.NMSS

Total Score

77

3.4.PDQ-39

Total Score

54

3.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

24

Part 4 Score

8

Part 5 Score

8

Part 6 Score

2

Part 7 Score

2

Part 8 Score

3

Part 9 Score

31

Part 10 Score

2

Part 11 Score

12

3.6.DSQ

Total Score

9

4.End of Treatment(32 week)
4.1.Physical Examination

Systolic Blood Pressure

128 mmHg

Heart Rate

67 t/s

Diastolic Blood Pressure

71.5 mmHg

Body Weight

59.8 kg

General Consultation
4.2.MDS-UPDRS
4.4.2.4.2.1、Part I

Total Score

10

4.4.2.4.2.2、Part II

Total Score

22

4.4.2.4.2.3、Part III

Total Score

56

Dyskinesias

Interfere with ratings

H&Y Stage

3

4.4.2.4.2.4、Part IV

Total Score

5

4.3.NMSS

Total Score

49

4.4.PDQ-39

Total Score

66

4.5.SF-36

Part 1 Score

4

Part 2 Score

2

Part 3 Score

18

Part 4 Score

11

Part 5 Score

9

Part 6 Score

2

Part 7 Score

6

Part 8 Score

4

Part 9 Score

32

Part 10 Score

2

Part 11 Score

10

4.6.DSQ

Total Score

7

5.Week 6 follow-up(38 week)
5.1.Physical Examination

Systolic Blood Pressure

140 mmHg

Diastolic Blood Pressure

77 mmHg

Heart Rate

66.5 t/s

Body Weight

58.7 kg

General Consultation
5.2.MDS-UPDRS
5.5.2.5.2.1、Part I

Total Score

12

5.5.2.5.2.2、Part II

Total Score

22

5.5.2.5.2.3、Part III

Total Score

58

Dyskinesias

Interfere with ratings

H&Y Stage

3

5.5.2.5.2.4、Part IV

Total Score

5

5.3.NMSS

Total Score

66

5.4.PDQ-39

Total Score

64

5.5.SF-36

Part 1 Score

4

Part 2 Score

3

Part 3 Score

19

Part 4 Score

12

Part 5 Score

10

Part 6 Score

2

Part 7 Score

2

Part 8 Score

2

Part 9 Score

34

Part 10 Score

4

Part 11 Score

8

5.6.DSQ

Total Score

7

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