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0.before the treament
0.1.Frequent seizure before the treament
0.2.The interictal epileptic discharge index of Electroencephalogram before treament

The interictal epileptic discharge index at sleep

46.3%

The interictal epileptic discharge index in awake

32.73%

0.3.the height before treament

The height Z-score

-0.59

0.4.the weight before treament

The weight Z-score

-1.22

0.5.Gesell Development Schedule Test before treament

language

32

fine motor

22

gross motor

23

adaptation

29

personal-social

8

0.6.Inclusion criteria

Age(6 months old--6 years old)

Yes

0.7.Exclusion criteria

with at least one situation as listed following

1.1 month after treatment
1.1.The interictal epileptic discharge index of Electroencephalogram

The interictal epileptic discharge index in awake

31.6%

The interictal epileptic discharge index at sleep

43.29%

1.2.Side-effect

side-effect

Vomiting
/
diarrhea

4.1.Frequent seizure
2.3 month after treatment
2.1.Frequent seizure

Seizure reduction

2.2.weight

The weight Z-score

-1.51

2.3.height

The height Z-score

-0.9

2.4.Gesell Development Schedule Test

gross motor

30

fine motor

32

adaptation

29

language

35

personal-social

14

2.5.side-effect

side-effect

constipation

3.6 month after treatment
3.1.Frequent seizure

Seizure reduction

3.2.weight

The weight Z-score

-1.11

3.3.height

The height Z-score

-0.76

3.4.Gesell Development Schedule Test

personal-social

29

adaptation

42

gross motor

28

language

49

fine motor

39

3.5.Side-effect

side-effect

4.12 month after treatment
4.1.Frequent seizure

Seizure reduction

4.2.weight

The weight Z-score

4.3.height

The height Z-score

4.4.Gesell Development Schedule Test

fine motor

39

gross motor

41

adaptation

67

language

52

personal-social

36

4.5.Side-effect

side-effect

5.18 month after treatment
5.1.Frequent seizure

Seizure reduction

5.2.weight

The weight Z-score

0.5

5.3.height

The height Z-score

-0.7

5.4.Gesell Development Schedule Test

adaptation

65

gross motor

53

language

57

fine motor

42

personal-social

37

5.5.Side-effect

side-effect