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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

70 years

Body Mass Index

22.41

2.Nutritional status

albumin

36 g/L

preaalbumin

230 mg/L

transferrin

0.85 g/L

3.liver function

Alanine aminotransferase

24 U/L

Total bilirubin

9 mmol/L

4.immunologic function

CD3

41.9 %

CD4

32.8 %

CD8

17.2 %

CD4/CD8

1.74

IgA

2.12 %

IgG

10.3 %

IgM

1.13 %

5.Inflammatory markers

C-reactive protein

2.8 mg/L

Interleukin 6

5.9 pg/L

3.pre-operation
1.Nutritional status

albumin

g/L

preaalbumin

mg/L

transferrin

g/L

2.liver function

alanine aminotransferase

U/L

Total bilirubin

mmol/L

3.immunologic function

CD3

%

CD4

%

CD8

%

CD4/CD8

IgA

g/L

IgG

g/L

IgM

g/L

4.Inflammatory markers

C-reactive protein

mg/L

Interleukin 6

pg/L

4.three days after surgery
1.Nutritional status

albumin

25 g/L

preaalbumin

200 mg/L

transferrin

1.65 g/L

2.liver function

Alanine aminotransferase

24 U/L

Total bilirubin

21 mmol/L

3.immunologic function

CD3

66.9 %

CD4

48.8 %

CD8

21.2 %

CD4/CD8

2.14

IgA

1.83 g/L

IgG

2.12 g/L

IgM

0.3 g/L

4.Inflammatory markers

C-reactive protein

15 mg/L

Interleukin 6

21.9 pg/L

5.seven days after surgery
1.Nutritional status

albumin

30 g/L

preaalbumin

162 mg/L

transferrin

1.9 g/L

2.liver function

Alanine aminotransferase

26 U/L

Total bilirubin

18 mmol/L

3.immunologic function

CD3

41.6 %

CD4

39 %

CD8

22.4 %

CD4/CD8

1.26

IgA

0.27 g/L

IgG

9.3 g/L

IgM

0.67 g/L

4.Inflammatory markers

C-reactive protein

8 mg/L

Interleukin 6

8.1 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

43185 yuan

hospital stays

15 Day