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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

69 years

Body Mass Index

21.05

2.Nutritional status

albumin

40 g/L

preaalbumin

273 mg/L

transferrin

2.1 g/L

3.liver function

Alanine aminotransferase

38 U/L

Total bilirubin

22 mmol/L

4.immunologic function

CD3

63.2 %

CD4

40.6 %

CD8

21.3 %

CD4/CD8

1.98

IgA

1.08 %

IgG

6.2 %

IgM

0.77 %

5.Inflammatory markers

C-reactive protein

4.6 mg/L

Interleukin 6

8.5 pg/L

3.pre-operation
1.Nutritional status

albumin

39 g/L

preaalbumin

228 mg/L

transferrin

2.06 g/L

2.liver function

alanine aminotransferase

28 U/L

Total bilirubin

20 mmol/L

3.immunologic function

CD3

57.1 %

CD4

44.1 %

CD8

20.4 %

CD4/CD8

2.16

IgA

1.37 g/L

IgG

8.75 g/L

IgM

0.95 g/L

4.Inflammatory markers

C-reactive protein

7 mg/L

Interleukin 6

2.6 pg/L

4.three days after surgery
1.Nutritional status

albumin

31 g/L

preaalbumin

225 mg/L

transferrin

1.86 g/L

2.liver function

Alanine aminotransferase

52 U/L

Total bilirubin

12 mmol/L

3.immunologic function

CD3

53.2 %

CD4

27.2 %

CD8

21.9 %

CD4/CD8

1.37

IgA

1.21 g/L

IgG

9.15 g/L

IgM

1.02 g/L

4.Inflammatory markers

C-reactive protein

21 mg/L

Interleukin 6

15.2 pg/L

5.seven days after surgery
1.Nutritional status

albumin

28 g/L

preaalbumin

275 mg/L

transferrin

1.56 g/L

2.liver function

Alanine aminotransferase

21 U/L

Total bilirubin

36 mmol/L

3.immunologic function

CD3

55.8 %

CD4

48.9 %

CD8

22.3 %

CD4/CD8

2.32

IgA

1.62 g/L

IgG

10.5 g/L

IgM

0.89 g/L

4.Inflammatory markers

C-reactive protein

15 mg/L

Interleukin 6

7.5 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

43906 yuan

hospital stays

22 Day