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1.Screening
1.Inclusion Criteria

Older than the age of 65

yes

according to gastric cancer guidelines diagnostic criteria of the national comprehensive cancer network (NCCN) in 2014, were diagnosed with stage II, III gastric cancer postoperative

yes

According to Nutritional Risk Screening 2002 (NRS 2002) of the European society of parenteral enteral nutrition, their global scoring were more than 3 points

yes

normal hepatic and renal function before surgery

yes

hormone, immunopotentiator or immunosuppressor were not administered half a year before surgery

yes

Without radiotherapy, and chemotherapy preoperative

yes

2.Exclusion Criteria

moderate anemia, hemoglobin< 90 g/L

no

severe hypoalbuminemia, albumin< 25 g/L

no

with at least one disease as listed following

metabolic and allergic diseases,Such as total triglyeride>2.26mmol or total cholesterol>6.2mmol/L

no

overweight patients, BMI>28

no

Special circumstances in the operation

2.hospital admission
1.General information

age

72 years

Body Mass Index

20.18

2.Nutritional status

albumin

39 g/L

preaalbumin

202 mg/L

transferrin

1.79 g/L

3.liver function

Alanine aminotransferase

28 U/L

Total bilirubin

20 mmol/L

4.immunologic function

CD3

49.5 %

CD4

26.8 %

CD8

16.3 %

CD4/CD8

1.79

IgA

0.43 %

IgG

5.8 %

IgM

0.67 %

5.Inflammatory markers

C-reactive protein

4.7 mg/L

Interleukin 6

9.8 pg/L

3.pre-operation
1.Nutritional status

albumin

31 g/L

preaalbumin

241 mg/L

transferrin

1.79 g/L

2.liver function

alanine aminotransferase

23 U/L

Total bilirubin

20 mmol/L

3.immunologic function

CD3

36 %

CD4

26.8 %

CD8

16.3 %

CD4/CD8

1.67

IgA

0.82 g/L

IgG

6.55 g/L

IgM

1.47 g/L

4.Inflammatory markers

C-reactive protein

4 mg/L

Interleukin 6

2.9 pg/L

4.three days after surgery
1.Nutritional status

albumin

29 g/L

preaalbumin

212 mg/L

transferrin

1.87 g/L

2.liver function

Alanine aminotransferase

18 U/L

Total bilirubin

33 mmol/L

3.immunologic function

CD3

56.5 %

CD4

30.4 %

CD8

23.4 %

CD4/CD8

1.14

IgA

0.6 g/L

IgG

8.8 g/L

IgM

0.85 g/L

4.Inflammatory markers

C-reactive protein

6 mg/L

Interleukin 6

10.2 pg/L

5.seven days after surgery
1.Nutritional status

albumin

29 g/L

preaalbumin

188 mg/L

transferrin

1.64 g/L

2.liver function

Alanine aminotransferase

15 U/L

Total bilirubin

11 mmol/L

3.immunologic function

CD3

49.9 %

CD4

40.4 %

CD8

23.4 %

CD4/CD8

1.78

IgA

0.98 g/L

IgG

8.7 g/L

IgM

0.73 g/L

4.Inflammatory markers

C-reactive protein

6 mg/L

Interleukin 6

7.2 pg/L

6.complications

infection

anastomotic leakage

7.Discharge summary

hospitalization costs

61768 yuan

hospital stays

20 Day